DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mur11Da and MMP8

DIOPT Version :9

Sequence 1:	NP_727652.3	Gene:	Mur11Da / 318139	FlyBaseID:	FBgn0052644	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	XP_011541136.1	Gene:	MMP8 / 4317	HGNCID:	7175	Length:	476	Species:	Homo sapiens

Alignment Length:	179	Identity:	36/179 - (20%)
Similarity:	56/179 - (31%)	Gaps:	53/179 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LSQGHGDDYLRF--PDPGNIPRYNQRPCGPRVCGKSGHCYRSFESICDFNDYNLKMIFSGQELFE 78
            :|||..|..:.|  .|.|:...::    ||.  |...|.::..:.|            .|...|:
Human   160 ISQGEADINIAFYQRDHGDNSPFD----GPN--GILAHAFQPGQGI------------GGDAHFD 206

  Fly    79 LTEPIYCQPSPPRTKLVDVGYYFNHRSLLVAQSQPSAYSSPIPRPSFTQNPKNIEHYDAYPSSDS 143
             .|..:...|......:...:.|.|...|...|.|.|...|              :| |:..:.:
Human   207 -AEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYP--------------NY-AFRETSN 255

  Fly   144 YG-PVQDYELPYPVWAFKRPQAPPRSPPVSYRPPYWYYPTRRPEITKPC 191
            |. |..|.:....::...       |.|:.        || .|...|||
Human   256 YSLPQDDIDGIQAIYGLS-------SNPIQ--------PT-GPSTPKPC 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mur11Da	NP_727652.3	None
MMP8	XP_011541136.1	PG_binding_1	45..95	CDD:279773
		Peptidase_M10	116..271	CDD:278824	28/144 (19%)
		ZnMc_MMP	116..271	CDD:239805	28/144 (19%)
		HX	285..473	CDD:238046	3/4 (75%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900