DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mur11Da and HPX

DIOPT Version :9

Sequence 1:	NP_727652.3	Gene:	Mur11Da / 318139	FlyBaseID:	FBgn0052644	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_000604.1	Gene:	HPX / 3263	HGNCID:	5171	Length:	462	Species:	Homo sapiens

Alignment Length:	152	Identity:	34/152 - (22%)
Similarity:	53/152 - (34%)	Gaps:	47/152 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 GDDYLRFPDP--GNI-PRYNQ------RPCGPRVCGKSGHCYRS--------------------- 55
            |:.:||| ||  |.: |||.:      .||..|     ||.:|:
Human   203 GNQFLRF-DPVRGEVPPRYPRDVRDYFMPCPGR-----GHGHRNGTGHGNSTHHGPEYMRCSPHL 261

  Fly    56 FESICDFNDYNLKMIFSGQELFEL--------TEPIYCQ-PSPPRTKLVDVGYYFNHRSLLVAQS 111
            ..|....:::.....|||...:.|        :.||..| |..|  ..||..:.:..:..||..:
Human   262 VLSALTSDNHGATYAFSGTHYWRLDTSRDGWHSWPIAHQWPQGP--SAVDAAFSWEEKLYLVQGT 324

  Fly   112 QPSAYSSPIPRPSFTQNPKNIE 133
            |...:.:.......:..||.:|
Human   325 QVYVFLTKGGYTLVSGYPKRLE 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mur11Da	NP_727652.3	None
HPX	NP_000604.1	HX	256..460	CDD:238046	18/93 (19%)
		Hemopexin 5	259..304		9/44 (20%)
		Hemopexin 6	305..352		9/44 (20%)
		Hemopexin 7	357..396
		Hemopexin 8	400..450
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	29..48
		O-glycosylated at one site	30..40
		HX	47..231	CDD:238046	10/28 (36%)
		Hemopexin 1	53..93
		Hemopexin 2	94..139
		Hemopexin 3	140..184
		Hemopexin 4	185..231		10/28 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900