DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mur11Da and Mmp20

DIOPT Version :9

Sequence 1:	NP_727652.3	Gene:	Mur11Da / 318139	FlyBaseID:	FBgn0052644	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_001100270.1	Gene:	Mmp20 / 300341	RGDID:	1308730	Length:	482	Species:	Rattus norvegicus

Alignment Length:	202	Identity:	43/202 - (21%)
Similarity:	65/202 - (32%)	Gaps:	63/202 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LRAFAFTVLLTALTLSQGHGDDYLRFP--DPGNIPRYNQRPCGPRVCGKSGHCYRSFESI---CD 61
            |.|::..|.|..:.::.|..|..:.|.  |.|:...::    |||  |...|.:...|.:   ..
  Rat   145 LHAWSTAVPLIFVRINSGEADIMISFETGDHGDSYPFD----GPR--GTLAHAFAPGEGLGGDTH 203

  Fly    62 F-NDYNLKMIFSGQELFELTEPIYCQPSPPRTKLVDVGYYFNHRSLLVAQSQPSAYSSPIPRPSF 125
            | |.....|..:|..||.:                 ..:.|.|...|...:.|||...|..:
  Rat   204 FDNAEKWTMGTNGFNLFTV-----------------AAHEFGHALGLGHSTDPSALMYPTYK--- 248

  Fly   126 TQNPKNIEHYDAYPSSD------SYGPVQDYELPYPVWAFKRPQAPPRSPPVSYRPPYWYYPTRR 184
            .|||....    .|..|      .|||.:.:               |..|.:.:.||:      :
  Rat   249 YQNPYRFH----LPKDDVKGIQALYGPRKTF---------------PGKPTMPHIPPH------K 288

  Fly   185 PEITKPC 191
            |.|...|
  Rat   289 PSIPDLC 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mur11Da	NP_727652.3	None
Mmp20	NP_001100270.1	PG_binding_1	39..94	CDD:279773
		Peptidase_M10	115..270	CDD:278824	33/154 (21%)
		ZnMc_MMP	115..270	CDD:239805	33/154 (21%)
		HX	292..464	CDD:238046	1/4 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900