DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mur11Da and Mmp15

DIOPT Version :9

Sequence 1:	NP_727652.3	Gene:	Mur11Da / 318139	FlyBaseID:	FBgn0052644	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_001099638.1	Gene:	Mmp15 / 291848	RGDID:	1308937	Length:	657	Species:	Rattus norvegicus

Alignment Length:	221	Identity:	54/221 - (24%)
Similarity:	69/221 - (31%)	Gaps:	71/221 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RAFAFTVLLTALTLSQGHGDD-----------YLRFPDPGNIPRYNQRPCGPRVCGKSGHCYRSF 56
            ||.|..::|.|   |..|||.           :..||.||              .|...|.
  Rat   188 RAEADIMVLFA---SGFHGDSSPFDGVGGFLAHAYFPGPG--------------LGGDTHF---- 231

  Fly    57 ESICDFNDYNLKMIFSGQELFELTEPIYCQPSPPRTKLVDVGYYFNHRSLLVAQSQPSAYSSPIP 121
                   |.:....||..:|..::           ..||.| :...|...|...|.|||..:|..
  Rat   232 -------DADEPWTFSSTDLHGIS-----------LFLVAV-HELGHALGLEHSSNPSAIMAPFY 277

  Fly   122 RPSFTQNPKNIEHYDAYPSSDSYGPVQDY---------ELPYPVWAFKRPQAPPRSPPVSYRPPY 177
            :...|.|.:       .|..|..|..|.|         ..|.|....:||..|...||   |||.
  Rat   278 QWMDTDNFQ-------LPEDDLRGIQQLYGSPDGKPQPTRPLPTVRPRRPGRPDHQPP---RPPQ 332

  Fly   178 WYYPTRRPE-ITKPCYGRTTTATKAP 202
            ..:|..:|| ..||.......||:.|
  Rat   333 PPHPGGKPERPPKPGPPPQPRATERP 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mur11Da	NP_727652.3	None
Mmp15	NP_001099638.1	PG_binding_1	42..102	CDD:279773
		Peptidase_M10	135..300	CDD:278824	35/158 (22%)
		ZnMc_MMP	135..300	CDD:239805	35/158 (22%)
		HX	363..555	CDD:238046
		DUF3377	<632..657	CDD:288690
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900