DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mur11Da and Prg4

DIOPT Version :9

Sequence 1:	NP_727652.3	Gene:	Mur11Da / 318139	FlyBaseID:	FBgn0052644	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_001099432.4	Gene:	Prg4 / 289104	RGDID:	1308976	Length:	1275	Species:	Rattus norvegicus

Alignment Length:	817	Identity:	211/817 - (25%)
Similarity:	272/817 - (33%)	Gaps:	275/817 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 NIPRYNQRPCGP---RVC----GKSGHCYRSF----ESICDFN---------DYNLKMIFSGQEL 76
            |...|.:  |.|   |||    ...|.|:.||    |..||..         |||...    :|:
  Rat    49 NCQHYME--CCPDFKRVCTTELSCKGRCFESFARGRECDCDSQCKQYGKCCADYNSFC----EEV 107

  Fly    77 FELTEPIYCQPSPPRT---------------------------KLVDVGYYFNHRSLLVAQSQPS 114
            ...|.|      ||:|                           |:|:........|  |:::|.|
  Rat   108 HNPTSP------PPKTAPPPPGASRTIKSTTKRSPKSPKKKTKKVVESEEITEEHS--VSENQES 164

  Fly   115 AYSSPI--------------------PRPSFTQNPKNIEHYDAYPSS---DSYGPVQDYELPYPV 156
            :.||..                    ..|....|.||.......|..   |..|...|...|
  Rat   165 SSSSSSSSSTIRKIKSSKNSANRELQKNPKVKDNKKNTPKKKPNPEPPVVDEAGSGLDNGEP--- 226

  Fly   157 WAFKRPQAPPRSPPVSYRPPYWYYPTRRPEIT-------KPCYGRTTTATKAPVTTT---TTTEA 211
                 ...||..||..:..     .|..|:.|       ||.....:..:|...:|:   ||.|.
  Rat   227 -----KLTPPPDPPTPHNK-----VTASPKTTAAKPVTPKPSLAPNSETSKEASSTSNKETTVET 281

  Fly   212 STTTTT----------------------------IEPSTST--NAAFTTT----TSTEASTTTTT 242
            ..||.|                            :||:::|  |:|.|||    |:|:....|||
  Rat   282 KETTETNKQSSASKKEKTTSAKETRSAENTSAKDVEPTSTTPKNSAPTTTKKPVTTTKEPVPTTT 346

  Fly   243 EG-----------------------------------------TTTSTEQTTTTKTTSPSTSTEI 266
            :|                                         ||....:.||.|.::|:|..|.
  Rat   347 KGPEPTSKEPAPTTPKEPELTIPKEPAPTTKKPAPTTPKEPAPTTPKEPEPTTPKESAPTTPKEP 411

  Fly   267 LTTTTE---LTTSTEPARTT--ESTTTTIADSASTITEQSNTT----EPTTTAEPTTTT------ 316
            ..||.:   .||..|||.||  |...||..:.|.|..:...||    .|||..||..||
  Rat   412 APTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTKKPEPTTPKEPAPTTPKEPAPTTPKEPAP 476

  Fly   317 ------EPTTTTEPTTTT----ENTTTTEPTTTT----EPTTTTEPTTTTEN----TTTTEPTTT 363
                  .|||..||..||    |:||..||..||    .|||..||..||..    ||..||..|
  Rat   477 NTPKEPAPTTPKEPAPTTPKEPESTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPT 541

  Fly   364 T----EPTTTTEPTTTTES----TTTTERVTNTDLTTTTTLLTTTKSQTSTDPSTTSSTT--EPS 418
            |    .|||..||..||..    ||..|.|..|.....:   ||.|....|.|...:.||  ||:
  Rat   542 TPKEPAPTTPKEPAPTTPKEPAPTTPKEPVPTTPKEPAS---TTPKEPAPTTPKEPAPTTPKEPA 603

  Fly   419 TTTNRSSSSTT----TTTVTTEPSTTTTVSSTTTTK--DPTTTESSTTTT---TVPTTLAESSTV 474
            .||.:..:.||    ..|...||:.||......|.|  :|||.:....||   ..|||..|.:.
  Rat   604 PTTPKEPAPTTPKEPAPTTPKEPALTTPKEPAPTPKEPEPTTPKEPAPTTPKEPAPTTPKEPAP- 667

  Fly   475 TTTLISKTTTSEPSTTSSTDSSTTTLTTDAPSTTTLSTETSTTINPAAVKPVTVEVT-------- 531
            ||.....|...||..|:..:.:.||....|| |||...|.||...|.:..|...|.|
  Rat   668 TTKKPELTIPKEPVPTTPKEPAPTTPKEPAP-TTTKKPELSTPKEPTSTNPKEPEPTLPKEPELT 731

  Fly   532 -----------NEDGQIVDFELA----AMAVNP-------ETGEPNCAEVTNVLITTGSRIVFQF 574
                       ..|..|.:...|    |:..||       ||.|.:..|:|.....|..:...|.
  Rat   732 LPEEPEPSNPETSDELIAELAEAPTPKALENNPKEPTVPTETPEVSKPEMTTAKEKTTEKDTTQT 796

  Fly   575 SGCIVARVASRTII------EPTTTSSTTVATTTQNT 605
            :..:..:..:.|.|      ||..:::|.:.:|.|:|
  Rat   797 TTTVTPKTTTETTIIPEETTEPRASTTTRITSTAQDT 833

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mur11Da	NP_727652.3	None
Prg4	NP_001099432.4	SO	26..68	CDD:197571	7/20 (35%)
		SO	67..108	CDD:197571	11/44 (25%)
		PHA03247	<315..724	CDD:223021	132/413 (32%)
		HX	1013..1274	CDD:238046
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900