DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mur11Da and Mmp21

DIOPT Version :9

Sequence 1:	NP_727652.3	Gene:	Mur11Da / 318139	FlyBaseID:	FBgn0052644	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_694423.1	Gene:	Mmp21 / 214766	MGIID:	2664387	Length:	568	Species:	Mus musculus

Alignment Length:	125	Identity:	31/125 - (24%)
Similarity:	42/125 - (33%)	Gaps:	48/125 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 QELFELTEPIYCQPSP-----PRTKLVDVGYYFNHRSLLVAQSQPSAYS-SPIPRP--------S 124
            :.||...:....:|||     |...|.|            |||....|. |.||.|        .
Mouse    25 ERLFHSRDRSDLEPSPLSQAKPIADLHD------------AQSFLLKYGWSEIPSPKESAGVPVG 77

  Fly   125 FT--QNPKNIEHYDAYPSSDSYGPVQDYELPYP-VWAFKRPQA-------PPR----SPP 170
            ||  |..:..:..:..|:|.        ||..| :.|..:|:.       |||    :||
Mouse    78 FTLAQAVRRFQKANRLPASG--------ELDSPTLAAMNKPRCGVPDTRLPPRAALPTPP 129

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mur11Da	NP_727652.3	None
Mmp21	NP_694423.1	PG_binding_1	48..107	CDD:279773	18/78 (23%)
		Cysteine switch. /evidence=ECO:0000250	110..117		1/6 (17%)
		Peptidase_M10	169..326	CDD:278824
		ZnMc_MMP	170..326	CDD:239805
		HX	328..544	CDD:238046
		Hemopexin 1	329..388
		Hemopexin 2	390..446
		Hemopexin 3	447..495
		Hemopexin 4	502..558
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900