DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mur11Da and Mmp12

DIOPT Version :9

Sequence 1:	NP_727652.3	Gene:	Mur11Da / 318139	FlyBaseID:	FBgn0052644	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_446415.2	Gene:	Mmp12 / 117033	RGDID:	620195	Length:	477	Species:	Rattus norvegicus

Alignment Length:	242	Identity:	49/242 - (20%)
Similarity:	70/242 - (28%)	Gaps:	72/242 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LTALTLSQGHGDDYLRFPDPGNIPRYNQRPCGPRVCGKSGHCYRSFESICDFNDYNLKMIFSGQE 75
            :|.|.....|||.| .|...|....:...| ||.:.| ..|...:......|...||.::    .
  Rat   167 ITILFAFGDHGDFY-DFDGKGGTLAHAFYP-GPGIQG-DAHFDEAETWTKSFQGTNLFLV----A 224

  Fly    76 LFELTEPI-----------------YCQPSPPRTKLVDVGYYFNHRSLLVAQSQPSAYSSPIPRP 123
            :.||...:                 |..|:..|....|:            .|..|.|.:|:..|
  Rat   225 VHELGHSLGLPHSNNPKSIMYPTYRYLHPNTFRLSADDI------------HSIQSLYGAPVKNP 277

  Fly   124 SFT---QNPKNIEHYDAYPSSDSYGPVQDYELPYPVWAF--KRPQAP--------------PRSP 169
            |.|   ..|..:.|...  |.|:...|.|....:..|.|  :.|.:|              |...
  Rat   278 SLTNPGSPPSTVCHQSL--SFDAVTTVGDKIFFFKDWFFWWRLPGSPATNITSISSMWPTIPSGI 340

  Fly   170 PVSYR------------PPYWYYPTRRPEITKPCYGRTTTATKAPVT 204
            ..:|.            ..||......||   |.|.|:..:...|.:
  Rat   341 QAAYEIGGRNQLFLFKDEKYWLINNLVPE---PHYPRSIHSLGFPAS 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mur11Da	NP_727652.3	None
Mmp12	NP_446415.2	PG_binding_1	41..95	CDD:279773
		Peptidase_M10	116..271	CDD:278824	24/122 (20%)
		ZnMc_MMP	116..271	CDD:239805	24/122 (20%)
		HX	293..477	CDD:238046	18/97 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900