DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32641 and DNAJB9

DIOPT Version :9

Sequence 1:	NP_727675.1	Gene:	CG32641 / 318136	FlyBaseID:	FBgn0052641	Length:	132	Species:	Drosophila melanogaster
Sequence 2:	NP_036460.1	Gene:	DNAJB9 / 4189	HGNCID:	6968	Length:	223	Species:	Homo sapiens

Alignment Length:	129	Identity:	45/129 - (34%)
Similarity:	66/129 - (51%)	Gaps:	23/129 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EDYYMILGVDHNATDEEIRRAYKRMALIYHPDKNKHPRTTAQFRKINEAFNVLSDASARRKYDAS 67
            :.||.||||..:|::.:|::|:.::|:.|||||||.|...|:||:|.||:..||||:.|::||.
Human    25 KSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDT- 88

  Fly    68 VMLSRRAHTTNNSHNSGGYQPNGSYEREMKTSDTFSTVCAVGGVLVGLFLGFGAFKALSGSNNN 131
              |...|.|:.......|    .|:|:....:            ...||..||.|    |.|.|
Human    89 --LGHSAFTSGKGQRGSG----SSFEQSFNFN------------FDDLFKDFGFF----GQNQN 130

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32641	NP_727675.1	DnaJ	4..65	CDD:278647	29/60 (48%)
DNAJB9	NP_036460.1	type 2 signal-anchor for ER localization	7..23
		DnaJ	26..>136	CDD:333066	45/128 (35%)
		Divergent targeting domain. /evidence=ECO:0000250\|UniProtKB:Q9QYI6	91..223		13/60 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145880
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004233
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740