Protein Alignment Lim1 and pb

DIOPT Version :10

• Sequence 1: NP_572505.1
• Gene: Lim1 / 31813
• FlyBaseID: FBgn0026411
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Alignment Length: 593
• Identity: 122/593 - (20%)
• Similarity: 181/593 - (30%)
• Gaps: 205/593 - (34%)

  Fly     2 AFGAVLHTSQHNIGRSEPPVGVGDPCAGCNKPILDKFLLNVLERAWHASCVRCCECLQPLTDKCF 66
            |.|.|......|:|     ||||.|....  |.....:.:|.|..|             :.:|..
  Fly   129 AIGGVGVNVNVNVG-----VGVGYPVGVV--PQTPDGMDSVPEYPW-------------MKEKKT 173

  Fly    67 SRESKLYCRNDFFRRYGTKCSGCGQG-------IAPSDLVRKPR-----------DKVFHLNCFT 113
            ||:|.               :...||       :..:.|.|:.|           :|.||.|.:.
  Fly   174 SRKSS---------------NNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYL 223

  Fly   114 CCICRKQLS-----TGEQLYVLDDNKFICKDDYLLGKAPSCGHNSLSDSLMGSASEDDDDDDPPH 173
            |...|.:::     |..|:.|...|:.:......|.|...   ....|||.|   :||..|...:
  Fly   224 CRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDD---EDNKDSLKG---DDDQSDSNSN 282

  Fly   174 LRATALGLGVLGPNGPDSAGGPLG------------------TSDISVQ-----------SMSTD 209
            .:.:..|..:...:.|||.....|                  |.:.|::           ::|..
  Fly   283 SKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNSSLETGISSNLMGSTTVSAS 347

  Fly   210 SKNTHDDSDQGSLDGDPDGRGDSQAENKSPDDANGSKRRGPRTTIKAKQLEVLKTAF---NQTPK 271
            :..:.|.|...|:..|.|....|..:.|..||....|:....|:.||       :.|   |.||.
  Fly   348 NVISADSSVASSVSLDEDIEESSPIKVKKKDDGQVIKKEAVSTSSKA-------SPFGYENSTPS 405

  Fly   272 PTRHIREQLAKETGLPMRVIQVWFQNKRSKERRMKQITSMGRPPFFGGARKMRGFPMNLSPGGLD 336
            .....|:..|...|           |..:.:       ::|:..|...|..: ..|..||.....
  Fly   406 LVSFRRDSDASAVG-----------NAPTSK-------AVGKKRFQSAANAI-ATPTPLSDSNSG 451

  Fly   337 DGPGFPYFAADAKFEFGYGGPFHPHDGPYFPGHPGGP-----------------MPFNAPGGPMD 384
            :|.|              |||    .|.||||:...|                 :|...   |.|
  Fly   452 NGSG--------------GGP----AGGYFPGYYPSPKQQQQVQQQQLHPQQQQLPQQQ---PQD 495

  Fly   385 HSGPIPMVNEFGLTPEATFLGQAGGPPMQLQSAVGPPPPPPPPSAEHLMAAAAAAAQQQAAQQQQ 449
            :.|...:  ||..:|.       ..|..:.|:..|....|.|.||..              .|..
  Fly   496 YYGKYDI--EFAASPH-------HNPHNKQQALHGEYLSPKPSSANF--------------HQNS 537

  Fly   450 QQQQQQQ---------------QQQQQNAQQAANQTQQQQQQN------GPRTNSPEFMSSANFS 493
            |||||..               ..|||:...|.:..|||..||      || .|.|...::..:.
  Fly   538 QQQQQNDHFYYNYNDTNGTPYLNHQQQHHHHAQHHQQQQHHQNHVADFEGP-VNGPSNFNNGAYY 601

  Fly   494 EPQNMQNE 501
            :..:.|.:
  Fly   602 DNMSFQQQ 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lim1	NP_572505.1	LIM1_Lhx1_Lhx5	27..78	CDD:188753	8/50 (16%)
		LIM2_Lhx1_Lhx5	86..141	CDD:188761	15/77 (19%)
		COG5576	185..324	CDD:227863	31/170 (18%)
		Homeodomain	248..304	CDD:459649	11/58 (19%)
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	12/55 (22%)