Protein Alignment Lim1 and Lim3

DIOPT Version :10

• Sequence 1: NP_572505.1
• Gene: Lim1 / 31813
• FlyBaseID: FBgn0026411
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001260559.1
• Gene: Lim3 / 35184
• FlyBaseID: FBgn0002023
• Length: 555
• Species: Drosophila melanogaster
• Alignment Length: 528
• Identity: 159/528 - (30%)
• Similarity: 218/528 - (41%)
• Gaps: 192/528 - (36%)

  Fly    27 CAGCNKPILDKFLLNVLERAWHASCVRCCECLQPLTDKCFSRESKLYCRNDFFRRYGTKCSGCGQ 91
            |.||::.|||:|:|.||||.|||.|::|.||...|.||||:|..:|:|:.|||:|||||||.|..
  Fly   122 CGGCHELILDRFILKVLERTWHAKCLQCSECHGQLNDKCFARNGQLFCKEDFFKRYGTKCSACDM 186

  Fly    92 GIAPSDLVRKPRDKVFHLNCFTCCICRKQLSTGEQLYVLDDNKFICKDDYLLGKAPSCGHNSLSD 156
            ||.|:.:||:.:|.|:||.||.|.:|.:.|:||::.|:::|.|.|||.||...||
  Fly   187 GIPPTQVVRRAQDNVYHLQCFLCAMCSRTLNTGDEFYLMEDRKLICKRDYEEAKA---------- 241

  Fly   157 SLMGSASEDDDDDDPPHLRATALGLGVLGPNGPDSAGGPLGTSDISVQSMSTDSKNTHDDSDQGS 221
                                                                  |..:.|   ||
  Fly   242 ------------------------------------------------------KGLYLD---GS 249

  Fly   222 LDGD-PDGRGDSQAENKSPDDANGSKRRGPRTTIKAKQLEVLKTAFNQTPKPTRHIREQLAKETG 285
            |||| |:.|                    |||||.|||||.||||:|.:|||.||:||||:::||
  Fly   250 LDGDQPNKR--------------------PRTTITAKQLETLKTAYNNSPKPARHVREQLSQDTG 294

  Fly   286 LPMRVIQVWFQNKRSKERRMKQITSMGRPPFFGGARKMRGFPMNLSPG----------------- 333
            |.|||:||||||:|:||:|:|:  ..||..:....|.|:|   |.||.
  Fly   295 LDMRVVQVWFQNRRAKEKRLKK--DAGRTRWSQYFRSMKG---NCSPRTDKFLDKDELKVDYDSF 354

  Fly   334 ---------------GLDDGPGFPYFAADAKFEFGYGGP--FHPHD---GPYFPGHPGGPMPFN- 377
                           |||:|.. |: :....:..|...|  :.|..   .|...||..|..|.|
  Fly   355 SHHDLSNDSYSTVNLGLDEGAS-PH-SIRGSYMHGSSSPSQYPPSSRSPPPVGQGHTFGSYPDNI 417

  Fly   378 -------APGGPM-------------------DHSGPIPMVNEFGLTPEATFLGQAGGPPMQLQS 416
                   |.|..:                   :.|.|.....:|..:|: ::||.:|.......:
  Fly   418 VYTNIDQAVGSSLHASKAHHRLHSSNNVSDLSNDSSPDQGYPDFPPSPD-SWLGDSGSTNTTSAN 481

  Fly   417 ------------------------AVGPPPPPPPPSAEHLMA--------AAAAAAQQQAAQQQQ 449
                                    :|...|.|..|...: .:        ..:.:....||||||
  Fly   482 NNANNNSSSSHNNNNSSGGGSGGVSVSTAPNPSAPGVHYXYSNLLLRYFEMQSRSLLLAAAQQQQ 546

  Fly   450 QQQQQQQQ 457
            |.|....|
  Fly   547 QHQPHSSQ 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lim1	NP_572505.1	LIM1_Lhx1_Lhx5	27..78	CDD:188753	27/50 (54%)
		LIM2_Lhx1_Lhx5	86..141	CDD:188761	25/54 (46%)
		COG5576	185..324	CDD:227863	54/139 (39%)
		Homeodomain	248..304	CDD:459649	39/55 (71%)
Lim3	NP_001260559.1	LIM1_Lhx3_Lhx4	122..173	CDD:188754	27/50 (54%)
		LIM2_Lhx3_Lhx4	181..236	CDD:188762	25/54 (46%)
		Homeodomain	257..313	CDD:459649	40/75 (53%)