DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Lim1 and HOXD10

DIOPT Version :9

Sequence 1:NP_572505.1 Gene:Lim1 / 31813 FlyBaseID:FBgn0026411 Length:505 Species:Drosophila melanogaster
Sequence 2:NP_002139.2 Gene:HOXD10 / 3236 HGNCID:5133 Length:340 Species:Homo sapiens


Alignment Length:137 Identity:39/137 - (28%)
Similarity:64/137 - (46%) Gaps:35/137 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   189 PDSAGG-PLGTS---DISVQSMSTDSKNTHDDSDQGSLDGDPDGRGDSQAEN----KSPDDANGS 245
            |::.|| |...|   ::||.|.....|.:.::.           :.|:...|    ||     |.
Human   219 PEAKGGLPEERSCLAEVSVSSPEVQEKESKEEI-----------KSDTPTSNWLTAKS-----GR 267

  Fly   246 KRRGPRTTIKAKQLEVLKT-AFNQTPKPTRHIREQLAKETGLPMRVIQVWFQNKR------SKER 303
            |:|.|.|  |.:.||:.|. .||.  ..||..|.:::|...|..|.:::||||:|      |:|.
Human   268 KKRCPYT--KHQTLELEKEFLFNM--YLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSREN 328

  Fly   304 RMKQITS 310
            |::::|:
Human   329 RIRELTA 335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Lim1NP_572505.1 LIM1_Lhx1_Lhx5 27..78 CDD:188753
LIM2_Lhx1_Lhx5 86..141 CDD:188761
COG5576 185..324 CDD:227863 39/137 (28%)
Homeobox 250..303 CDD:278475 20/59 (34%)
HOXD10NP_002139.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 200..268 14/64 (22%)
Homeobox 269..323 CDD:395001 20/57 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.