Protein Alignment Lim1 and lhx5

DIOPT Version :10

• Sequence 1: NP_572505.1
• Gene: Lim1 / 31813
• FlyBaseID: FBgn0026411
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_571293.1
• Gene: lhx5 / 30465
• ZFINID: ZDB-GENE-980526-484
• Length: 399
• Species: Danio rerio
• Alignment Length: 463
• Identity: 202/463 - (43%)
• Similarity: 247/463 - (53%)
• Gaps: 134/463 - (28%)

  Fly    27 CAGCNKPILDKFLLNVLERAWHASCVRCCECLQPLTDKCFSRESKLYCRNDFFRRYGTKCSGCGQ 91
            ||||.:||||:||||||:|||||.||:||||...||:|||||:.||||:.|||||:||||:||.|
Zfish     5 CAGCERPILDRFLLNVLDRAWHAKCVQCCECNCNLTEKCFSRDGKLYCKIDFFRRFGTKCAGCLQ 69

  Fly    92 GIAPSDLVRKPRDKVFHLNCFTCCICRKQLSTGEQLYVLDDNKFICKDDYL---------LGKAP 147
            ||:||||||:.|.||||||||||.:|.|||||||:|||:|:|||:||:|||         |....
Zfish    70 GISPSDLVRRARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKEDYLSASAIKEVNLNSVS 134

  Fly   148 SCGHNSLSDSLMGSASEDDDDDDPPHLRATALGLGVLGPNGPDSAGGPLGTSDISVQSMSTDSKN 212
            ||...|||..|.....:|..:.|                                 .|.|:| |:
Zfish   135 SCTDRSLSPDLPDQIQDDTKETD---------------------------------NSTSSD-KD 165

  Fly   213 THDDSDQGSLDGDPDGRGDSQAENKSPDDANGSKRRGPRTTIKAKQLEVLKTAFNQTPKPTRHIR 277
            |::                    |::.:..:.:|||||||||||||||.||.||..|||||||||
Zfish   166 TNN--------------------NENEEQNSCTKRRGPRTTIKAKQLETLKAAFVATPKPTRHIR 210

  Fly   278 EQLAKETGLPMRVIQVWFQNKRSKERRMKQITSMG--RPPFFGGARKMRGFPMNLSPGGLDD--- 337
            ||||:||||.||||||||||:|||||||||::::|  |..||.|.|:||  |:.   |.|:|
Zfish   211 EQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRGPRRMR--PLG---GRLEDPDI 270

  Fly   338 -GP-GFPYFAADAKFEFGYGGP-----FHPHDGPYFPGH----------------PGGPM----- 374
             || |:.|:   .:::..|.||     |.||..|....|                .|||:
Zfish   271 MGPGGYSYY---GEYQGDYYGPVVNYDFFPHGPPSSQAHSPAESPYLLSSGSGALEGGPVSAHHP 332

  Fly   375 ---------------PFNAPG--GPMDHSGPIPMVNEFGLTPEATFLGQAGGPPMQLQSAVGPPP 422
                           |...||  ||: ||.|   ..|.|.|         |.||..|.:......
Zfish   333 SDDQRFTDMISHADTPSPEPGMTGPL-HSNP---QGEGGFT---------GSPPFPLANNTSYSG 384

  Fly   423 PPPPPSAE 430
            |...|..|
Zfish   385 PMSHPGQE 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lim1	NP_572505.1	LIM1_Lhx1_Lhx5	27..78	CDD:188753	36/50 (72%)
		LIM2_Lhx1_Lhx5	86..141	CDD:188761	40/54 (74%)
		COG5576	185..324	CDD:227863	67/140 (48%)
		Homeodomain	248..304	CDD:459649	48/55 (87%)
lhx5	NP_571293.1	LIM1_Lhx1_Lhx5	5..56	CDD:188753	36/50 (72%)
		LIM2_Lhx1_Lhx5	64..119	CDD:188761	40/54 (74%)
		COG5576	126..>242	CDD:227863	70/169 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	136..185		18/102 (18%)
		Homeodomain	181..237	CDD:459649	48/55 (87%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	301..399		23/105 (22%)