Protein Alignment Lim1 and lhx1a

DIOPT Version :9

• Sequence 1: NP_572505.1
• Gene: Lim1 / 31813
• FlyBaseID: FBgn0026411
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_571291.1
• Gene: lhx1a / 30463
• ZFINID: ZDB-GENE-980526-347
• Length: 405
• Species: Danio rerio
• Alignment Length: 504
• Identity: 216/504 - (42%)
• Similarity: 257/504 - (50%)
• Gaps: 127/504 - (25%)

  Fly    27 CAGCNKPILDKFLLNVLERAWHASCVRCCECLQPLTDKCFSRESKLYCRNDFFRRYGTKCSGCGQ 91
            ||||.:||||:||||||:||||..||:||||...||:||||||.||||:||||||:||||:||.|
Zfish     4 CAGCERPILDRFLLNVLDRAWHIKCVQCCECKCNLTEKCFSREGKLYCKNDFFRRFGTKCAGCAQ 68

  Fly    92 GIAPSDLVRKPRDKVFHLNCFTCCICRKQLSTGEQLYVLDDNKFICKDDYLLGKAPSCGHNSLSD 156
            ||:|:||||:.|.||||||||||.:|.|||||||:||::|:|||:||||||
Zfish    69 GISPNDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKDDYL-------------- 119

  Fly   157 SLMGSASEDDDDDDPPHLRATALGLGVLGPNGPDSAGGPLGTSDISVQSMSTDSKNTHDDSDQGS 221
                                       ...||.||  ..|..:..|..|:|.||::...|..:
Zfish   120 ---------------------------SNTNGKDS--NLLSVTACSDPSLSPDSQDQLQDDVK-- 153

  Fly   222 LDGDPDGRGDSQAENKSPDDAN-GSKRRGPRTTIKAKQLEVLKTAFNQTPKPTRHIREQLAKETG 285
             |.:.....|.:..|...||.| |.|||||||||||||||.||.||..|||||||||||||:|||
Zfish   154 -DAEIANLSDKETGNNENDDQNLGGKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETG 217

  Fly   286 LPMRVIQVWFQNKRSKERRMKQITSMG--RPPFFGGARKMRGFPMNLSPGGL-DDGPGFPYFAAD 347
            |.||||||||||:|||||||||::::|  |..||...|:||.....|.||.| .:|| |.|:...
Zfish   218 LNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRTLVDRLEPGELIPNGP-FSYYGDY 281

  Fly   348 AKFEFGYGGPFH-------------PHDGPYFPGHPGGPMPFNAPGGPMDHSGPIPMVNEFGLTP 399
            ....:|.||.:.             |.|.|:.|.  .||.  ..|.|.|||  |||     |..|
Zfish   282 QSEYYGPGGNYDFFPQGPPSSQAQTPVDLPFVPS--SGPT--GTPLGGMDH--PIP-----GHHP 335

  Fly   400 EATFLGQAGGPPMQLQSAVGPPPPPPPPSAEHLMAAAAAAAQQQAAQQQQQQQQQQQQQQQQNAQ 464
            .:..  |.....|.......|.|.|..|...|.|::...
Zfish   336 SSEV--QRFSDIMSHHPGDSPSPEPGIPGPLHSMSSDVF-------------------------- 372

  Fly   465 QAANQTQQQQQQNGPRTNSPEFMS--------SANFSEPQNMQNEGLVW 505
                         ||   ||.|.|        |.:.|.|.:..|||.||
Zfish   373 -------------GP---SPSFTSLSLNGSGYSNHLSHPPSEMNEGTVW 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lim1	NP_572505.1	LIM1_Lhx1_Lhx5	27..78	CDD:188753	37/50 (74%)
		LIM2_Lhx1_Lhx5	86..141	CDD:188761	39/54 (72%)
		COG5576	185..324	CDD:227863	78/141 (55%)
		Homeobox	250..303	CDD:278475	45/52 (87%)
lhx1a	NP_571291.1	LIM1_Lhx1_Lhx5	4..55	CDD:188753	37/50 (74%)
		LIM2_Lhx1_Lhx5	63..118	CDD:188761	39/54 (72%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	158..184		11/25 (44%)
		Homeobox	182..235	CDD:278475	45/52 (87%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	296..373		24/128 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592802
Domainoid	1	1.000	106	1.000	Domainoid score	I6502
eggNOG	1	0.900	-	-		E33208_3B9QY
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4068
Inparanoid	1	1.050	341	1.000	Inparanoid score	I2321
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1070389at2759
OrthoFinder	1	1.000	-	-		FOG0002932
OrthoInspector	1	1.000	-	-		otm26116
orthoMCL	1	0.900	-	-		OOG6_105769
Panther	1	1.100	-	-	O	PTHR24208
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2608
SonicParanoid	1	1.000	-	-		X1931
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.790