Protein Alignment Lim1 and lhx3

DIOPT Version :10

• Sequence 1: NP_572505.1
• Gene: Lim1 / 31813
• FlyBaseID: FBgn0026411
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: XP_073805886.1
• Gene: lhx3 / 30455
• ZFINID: ZDB-GENE-980526-131
• Length: 411
• Species: Danio rerio
• Alignment Length: 477
• Identity: 143/477 - (29%)
• Similarity: 208/477 - (43%)
• Gaps: 177/477 - (37%)

  Fly    27 CAGCNKPILDKFLLNVLERAWHASCVRCCECLQPLTDKCFSRESKLYCRNDFF------------ 79
            |||||:.|:|:|:|.||:|.||:.|::|.:|...|.||||||...:||::|||
Zfish    28 CAGCNQHIVDRFILKVLDRHWHSKCLKCSDCQSQLADKCFSRGDSVYCKDDFFKSPLTRVCLCFV 92

  Fly    80 -RRYGTKCSGCGQGIAPSDLVRKPRDKVFHLNCFTCCICRKQLSTGEQLYVLDDNKFICKDDYLL 143
             ||:||||:.|.|||.|:.:||:.:|.|:||:||.|.:|::||:||::.|:::|::.:||.||
Zfish    93 SRRFGTKCAACQQGIPPTQVVRRAQDFVYHLHCFACIVCKRQLATGDEYYLMEDSRLVCKADY-- 155

  Fly   144 GKAPSCGHNSLSDSLMGSASEDDDDDDPPHLRATALGLGVLGPNGPDSAGGPLGTSDISVQSMST 208
                                                                             
Zfish   156 ----------------------------------------------------------------- 155

  Fly   209 DSKNTHDDSDQGSLDGDPDGRGDSQAENKSPDDANGSKRRGPRTTIKAKQLEVLKTAFNQTPKPT 273
                                      |.....:|:.:.:| |||||.|||||.||.|:|.:|||.
Zfish   156 --------------------------ETAKQREADSTAKR-PRTTITAKQLETLKNAYNNSPKPA 193

  Fly   274 RHIREQLAKETGLPMRVIQVWFQNKRSKERRMKQITSMGRP---PFFGGARKMRGFPMNLSPGGL 335
            ||:||||:.||||.|||:||||||:|:||:|:|:  ..||.   .:|...::.||...:......
Zfish   194 RHVREQLSTETGLDMRVVQVWFQNRRAKEKRLKK--DAGRQRWGQYFRNMKRSRGSSKSDKDSTQ 256

  Fly   336 DDGPGFPYFAADAKFEF---------GY------------------GG----------------- 356
            :||     ..:||:..|         |:                  ||
Zfish   257 EDG-----MDSDAEVSFTDEPPMSDLGHSNGIYSSLSESSPALSRQGGNHPAFPLEHGAIIPSQE 316

  Fly   357 PFH------PHDGPYFPGHPGGPMPFNAP---GGPMDHSGPIPMVNEFG---LTPEATFLGQAGG 409
            |:|      |:..|..|| |..|:|.:.|   ......|| :|||.:.|   :||....:....|
Zfish   317 PYHDIQASSPYSLPQSPG-PLQPLPRHQPLISSLVYPESG-LPMVGQSGGQNMTPGVRMMAAGNG 379

  Fly   410 PPMQLQ--SAVGPPPPPPPPSA 429
            |...|.  |:.|.|..|..|::
Zfish   380 PSSDLSTGSSGGYPDFPASPAS 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lim1	NP_572505.1	LIM1_Lhx1_Lhx5	27..78	CDD:188753	26/50 (52%)
		LIM2_Lhx1_Lhx5	86..141	CDD:188761	24/54 (44%)
		COG5576	185..324	CDD:227863	47/141 (33%)
		Homeodomain	248..304	CDD:459649	40/55 (73%)
lhx3	XP_073805886.1	None