DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lim1 and hoxd10a

DIOPT Version :9

Sequence 1:	NP_572505.1	Gene:	Lim1 / 31813	FlyBaseID:	FBgn0026411	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_571241.2	Gene:	hoxd10a / 30404	ZFINID:	ZDB-GENE-990415-116	Length:	332	Species:	Danio rerio

Alignment Length:	194	Identity:	46/194 - (23%)
Similarity:	82/194 - (42%)	Gaps:	41/194 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 PSCGHNSLSDSLMGSASEDDDDDDPPHLRATALGLGVLGPNGPDS----------------AGGP 195
            |..|:..||.: ..:|...|.|::......|.:.|....|....:                :..|
Zfish   145 PVPGYFRLSQT-YATAKNPDYDNETMSPNTTLMQLNRATPKAQSTPFVEVEKKLAHDRDTRSSSP 208

  Fly   196 LGTSDISVQSMSTDSKNTHDDSDQGSLDGDPD--GRGDSQAENKSPDD-----ANGSKRRGPRTT 253
            ..:.:..|.::  :.||...::...|    |:  .|...:::|.:|..     .:|.|:|.|.|
Zfish   209 AQSPEPKVSTL--EEKNCSTEASVSS----PELPHREGKESKNDTPTSNWLTAKSGRKKRCPYT- 266

  Fly   254 IKAKQLEVLKT-AFNQTPKPTRHIREQLAKETGLPMRVIQVWFQNKR------SKERRMKQITS 310
             |.:.||:.|. .||.  ..||..|.:::|...|..|.:::||||:|      |:|.|::::||
Zfish   267 -KHQTLELEKEFLFNM--YLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTS 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lim1	NP_572505.1	LIM1_Lhx1_Lhx5	27..78	CDD:188753
		LIM2_Lhx1_Lhx5	86..141	CDD:188761
		COG5576	185..324	CDD:227863	37/156 (24%)
		Homeobox	250..303	CDD:278475	20/59 (34%)
hoxd10a	NP_571241.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..261		10/72 (14%)
		COG5576	204..>321	CDD:227863	33/126 (26%)
		Homeobox	261..314	CDD:278475	20/56 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910