Protein Alignment Lim1 and Lhx3

DIOPT Version :10

• Sequence 1: NP_572505.1
• Gene: Lim1 / 31813
• FlyBaseID: FBgn0026411
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: XP_038962056.2
• Gene: Lhx3 / 170671
• RGDID: 71078
• Length: 431
• Species: Rattus norvegicus
• Alignment Length: 502
• Identity: 143/502 - (28%)
• Similarity: 206/502 - (41%)
• Gaps: 198/502 - (39%)

  Fly    16 RSEPPVGVGDPCAGCNKPILDKFLLNVLERAWHASCVRCCECLQPLTDKCFSRESKLYCRNDFFR 80
            |.|.|:     ||||::.|||:|:|..|:|.||:.|::|.:|..||.::||||...:||::|||:
  Rat    30 RREIPM-----CAGCDQHILDRFILKALDRHWHSKCLKCSDCHVPLAERCFSRGESVYCKDDFFK 89

  Fly    81 RYGTKCSGCGQGIAPSDLVRKPRDKVFHLNCFTCCICRKQLSTGEQLYVLDDNKFICKDDYLLGK 145
            |:||||:.|..||.|:.:||:.:|.|:||:||.|.:|::||:||::.|:::|::.:||.||
  Rat    90 RFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY---- 150

  Fly   146 APSCGHNSLSDSLMGSASEDDDDDDPPHLRATALGLGVLGPNGPDSAGGPLGTSDISVQSMSTDS 210
                                                                             
  Rat   151 ----------------------------------------------------------------- 150

  Fly   211 KNTHDDSDQGSLDGDPDGRGDSQAENKSPDDANGSKRRGPRTTIKAKQLEVLKTAFNQTPKPTRH 275
                                    |.....:|..:.:| |||||.|||||.||:|:|.:|||.||
  Rat   151 ------------------------ETAKQREAEATAKR-PRTTITAKQLETLKSAYNTSPKPARH 190

  Fly   276 IREQLAKETGLPMRVI-----------------------------QVWFQNKRSKERRMKQITSM 311
            :||||:.||||.|||:                             ||||||:|:||:|:|:  ..
  Rat   191 VREQLSSETGLDMRVVQVSARSRPPAPEGARAPREAGQPLTIPTPQVWFQNRRAKEKRLKK--DA 253

  Fly   312 GRP---PFFGGARKMRGF-----------------------PMNLSPG---GLDDGPGFPYFAAD 347
            ||.   .:|...::.||.                       |.....|   ||....|.|..|..
  Rat   254 GRQRWGQYFRNMKRSRGSSKSDKDSIQEGQDSDAEVSFTDEPSMADMGTANGLYSSLGEPAPALG 318

  Fly   348 ------AKFEFGYGGPFHPHDGPYF----PGHPGGPMPFNAPGGPMDHSGPIPMVN-------EF 395
                  ..|...:||...|..   |    ||.|.|..|  :|..|....||.|:::       ..
  Rat   319 RPVGGLGSFTLEHGGLAGPEQ---FRELRPGSPYGIPP--SPAAPQSLPGPQPLLSSLVYPDTNL 378

  Fly   396 GLTPEATFLGQAGGPP-------------MQLQSAVGPPPPPPPPSA 429
            ||.|.    |..||||             :..:|:.|.|..|..|::
  Rat   379 GLVPS----GPPGGPPPMRVLAGNGPSSDLSTESSGGYPDFPASPAS 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lim1	NP_572505.1	LIM1_Lhx1_Lhx5	27..78	CDD:188753	24/50 (48%)
		LIM2_Lhx1_Lhx5	86..141	CDD:188761	23/54 (43%)
		COG5576	185..324	CDD:227863	47/170 (28%)
		Homeodomain	248..304	CDD:459649	40/84 (48%)
Lhx3	XP_038962056.2	None