DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lim1 and Hoxd10

DIOPT Version :9

Sequence 1:	NP_572505.1	Gene:	Lim1 / 31813	FlyBaseID:	FBgn0026411	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	XP_006498852.1	Gene:	Hoxd10 / 15430	MGIID:	96202	Length:	410	Species:	Mus musculus

Alignment Length:	137	Identity:	39/137 - (28%)
Similarity:	64/137 - (46%)	Gaps:	35/137 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 PDSAGG-PLGTS---DISVQSMSTDSKNTHDDSDQGSLDGDPDGRGDSQAEN----KSPDDANGS 245
            |::.|| |...|   ::||.|.....|.:.::.           :.|:...|    ||     |.
Mouse   289 PEAKGGLPEDRSCLAEVSVSSPEVQEKESKEEI-----------KSDTPTSNWLTAKS-----GR 337

  Fly   246 KRRGPRTTIKAKQLEVLKT-AFNQTPKPTRHIREQLAKETGLPMRVIQVWFQNKR------SKER 303
            |:|.|.|  |.:.||:.|. .||.  ..||..|.:::|...|..|.:::||||:|      |:|.
Mouse   338 KKRCPYT--KHQTLELEKEFLFNM--YLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSREN 398

  Fly   304 RMKQITS 310
            |::::|:
Mouse   399 RIRELTA 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lim1	NP_572505.1	LIM1_Lhx1_Lhx5	27..78	CDD:188753
		LIM2_Lhx1_Lhx5	86..141	CDD:188761
		COG5576	185..324	CDD:227863	39/137 (28%)
		Homeobox	250..303	CDD:278475	20/59 (34%)
Hoxd10	XP_006498852.1	Homeobox	339..393	CDD:365835	20/57 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910