Protein Alignment Lim1 and lhx1

DIOPT Version :9

• Sequence 1: NP_572505.1
• Gene: Lim1 / 31813
• FlyBaseID: FBgn0026411
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001093698.1
• Gene: lhx1 / 100101708
• XenbaseID: XB-GENE-482482
• Length: 409
• Species: Xenopus tropicalis
• Alignment Length: 436
• Identity: 208/436 - (47%)
• Similarity: 253/436 - (58%)
• Gaps: 93/436 - (21%)

  Fly    27 CAGCNKPILDKFLLNVLERAWHASCVRCCECLQPLTDKCFSRESKLYCRNDFFRRYGTKCSGCGQ 91
            ||||.:||||:||||||:||||..||:||||...||:||||||.||||:||||||:||||:||.|
 Frog     4 CAGCERPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRRFGTKCAGCAQ 68

  Fly    92 GIAPSDLVRKPRDKVFHLNCFTCCICRKQLSTGEQLYVLDDNKFICKDDYLLGKAPSCGHNSLSD 156
            ||:||||||:.|.||||||||||.:|.|||||||:||::|:|||:||:|||...  :..:|:..:
 Frog    69 GISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLNNN--NNNNNAAKE 131

  Fly   157 ----SLMGSASEDDDDDDPPHLRATALGLGVLGPNGPDSAGGPLGTSDISVQSMSTDSKNTHDDS 217
                |:.||        ||.           |.|...|    ||          ..|:|    ||
 Frog   132 NSFISVTGS--------DPS-----------LSPESQD----PL----------QDDAK----DS 159

  Fly   218 DQGSLDGDPDGRGDSQAENKSPDDAN-GSKRRGPRTTIKAKQLEVLKTAFNQTPKPTRHIREQLA 281
            :..::       .|.:|.....||.| |:|||||||||||||||.||.||..|||||||||||||
 Frog   160 ESANI-------SDKEAGVNENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLA 217

  Fly   282 KETGLPMRVIQVWFQNKRSKERRMKQITSMG--RPPFFGGARKMRGFPMNLSPGGL-DDGPGFPY 343
            :||||.||||||||||:|||||||||::::|  |..||...|:||.....|.||.| .:||
 Frog   218 QETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGP---- 278

  Fly   344 FAADAKFEFGYGGPFHPHDGPYFP-GHPGG------PMPF-------NAPGGPMDHSGPIPMVNE 394
            |:....::..|.||...:|  :|| |.|..      .:||       ..|.|.|||  |||
 Frog   279 FSFYGDYQSEYYGPGSNYD--FFPQGPPSSQAQTPVDLPFVPSSGPAGTPLGAMDH--PIP---- 335

  Fly   395 FGLTPEA---TFLGQAGGPPMQLQSAVGPPPPPPP--PSAEHLMAA 435
             |..|.:   .|......||       |..|.|.|  |.:.|.|:|
 Frog   336 -GHHPSSDAQRFTDIMSHPP-------GDSPSPEPNLPGSMHSMSA 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lim1	NP_572505.1	LIM1_Lhx1_Lhx5	27..78	CDD:188753	37/50 (74%)
		LIM2_Lhx1_Lhx5	86..141	CDD:188761	39/54 (72%)
		COG5576	185..324	CDD:227863	74/141 (52%)
		Homeobox	250..303	CDD:278475	45/52 (87%)
lhx1	NP_001093698.1	LIM1_Lhx1_Lhx5	4..55	CDD:188753	37/50 (74%)
		LIM2_Lhx1_Lhx5	63..118	CDD:188761	39/54 (72%)
		Homeobox	186..240	CDD:365835	46/53 (87%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	105	1.000	Domainoid score	I6564
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4068
Inparanoid	1	1.050	334	1.000	Inparanoid score	I2367
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1070389at2759
OrthoFinder	1	1.000	-	-		FOG0002932
OrthoInspector	1	1.000	-	-		otm47631
Panther	1	1.100	-	-	O	PTHR24208
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2608
SonicParanoid	1	1.000	-	-		X1931
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.100