Protein Alignment drd and CG14219

DIOPT Version :10

• Sequence 1: NP_001033845.1
• Gene: drd / 318102
• FlyBaseID: FBgn0260006
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_608322.1
• Gene: CG14219 / 32951
• FlyBaseID: FBgn0031033
• Length: 724
• Species: Drosophila melanogaster
• Alignment Length: 838
• Identity: 208/838 - (24%)
• Similarity: 347/838 - (41%)
• Gaps: 179/838 - (21%)

  Fly     1 MSRMSHMLALLLVLIASSQALEGVVQPTCNLKDNCNLGDNLLAGTNSASDAGDVSADKLESKIAS 65
            |.|::.:|.|.|:.:|.|.              |..: .|:.|.||:......::..   ...:|
  Fly     1 MVRLAFILGLGLLALAKSV--------------NAQM-TNIFAMTNTKLLTEHIAGG---DHYSS 47

  Fly    66 IFEDKVNYSLKLFADDATTTILEYQTANLSQLHAVTPGNYTIHQMEQAEDDDDQVEEDERAYLYN 130
            ||..: ..|::.|...|..| ||..|||         .|..|..::..|
  Fly    48 IFNTR-RLSVEFFEHYANVT-LEDLTAN---------SNSRIPSLQDLE---------------- 85

  Fly   131 IGKRFLAITQPFDAARNPDASTLCRRQMHQFLNALDNFDLWALKMHDSSGKLNSGILNGNINQPG 195
                                   |...:......|.:|..|||||.||.|.|.||:|.||....|
  Fly    86 -----------------------CLADLALLSKDLSSFKFWALKMIDSWGLLPSGMLAGNWWNLG 127

  Fly   196 DFDQCLGIQQRMNQDQDAGQDQDGDSIIRGQYCLAYAQP---VLPHNSKRLKSFFKLIQSHGPFK 257
            :||:|:.|...:.....          |:|:||:....|   :||  ...|||
  Fly   128 NFDECIAIDHAVTSSHS----------IKGKYCITKLTPAPSLLP--ILALKS------------ 168

  Fly   258 SEFNDPGHRVPRYSLINWGLCVPSGCSARDVEYSVAEYLGNQTASTGITFNVR-VEPQMCQVRDQ 321
                              .:|.|:.|||.::: ::...|..:..:..|..:|: |..:.||...:
  Fly   169 ------------------AVCFPATCSAANMD-TMLRRLFQKLLTVEIDADVQIVAEETCQTAVK 214

  Fly   322 RPWDRNTTWAVRFFLLVLSVAVLSTIYDR-STKSQPKQNPWFTAFSLDKNLRWLF---STSSAPG 382
            :|:|....:.:....::.::..:.||:|. ..|.:...:|...|||...|.|.||   .|.:.|.
  Fly   215 KPYDGLAIFTIVIVSILGAIVGVCTIFDYFFCKDEKTIHPVVEAFSARANSRALFRIVDTKANPN 279

  Fly   383 DIEAVHGIRFLNAIMLIFSHKSMAMFFNPYNNRTAMSESLGQPWTVIGRAASLYTDPFLLFSG-M 446
            .|:.:||||.|:.|.:::.|..|.:..:|..|...:...:...:::..:.|....|.|...|| :
  Fly   280 VIDCLHGIRCLSFIWVVYGHDYMVLATSPNINMGYLLTWINSFYSLFVKHAVYAVDSFFFLSGLL 344

  Fly   447 LTSYSLFGRLMKQQPIRLKNEYISRLMRIVPPLAALILFCTYVLPLWGSGPQWNLVVGHHADICK 511
            |...:|......:..:.:...|:.|.:|:.|.||..|||...:||||.|||....:.......|:
  Fly   345 LVVIALRSMDRTKGKLNIPLMYLHRYLRLTPILAIAILFYMKILPLWESGPLKGSISFDDYSACE 409

  Fly   512 KNWWRNLLFIHNYFGFSEMCLTHTHHLGIDTELFAVAPLLILALWRWPRR---GLFALLLLCTVG 573
            ..|:..||::.|| ....:||:|:.:|.:|.:|:..||.|::.|::|.::   |:|.|:||.
  Fly   410 STWYWTLLYVQNY-ATDSLCLSHSWYLAVDMQLYIFAPFLLICLYKWGKKAAAGIFVLMLLL--- 470

  Fly   574 TAARYYTTIVNQLS--------NYIYFGTNIQRLFRTADYMYSFPPHRSTVYIMGILLGYVL--R 628
            ....:...::|.||        ..:|:.|..                |::.|::|||.||.|  .
  Fly   471 AGCLFSIMVINDLSLGSGGDSMRKLYYATQT----------------RASPYLIGILFGYFLHTN 519

  Fly   629 KYQNARLSSLQLRLGWLVATVCVLASLLGPAPMGDINYVYNS-----THAAIYAAFAPIAWCLFF 688
            :.::.:|:.|.:.||||:|...:.:.|..         :|..     ...|.|.:...|||.|..
  Fly   520 RGKDFKLNRLAVLLGWLIALSLIASCLFS---------IYGQNTLPIVEEAFYVSLTRIAWPLGL 575

  Fly   689 SWIVFVSHNGYTNKLTKLFAWRGFQVSTKLSYAIYLTQFPVFFFNV-GRRRHIHHYYNFVSIILD 752
            .|:||...:||......|.:...:|..::|||:.|:  |.:|..:: |...|...|::...::|.
  Fly   576 CWVVFACMHGYGGLANSLLSSPLWQPLSRLSYSAYI--FHMFIESLNGGITHTSTYFSDYQVMLR 638

  Fly   753 -TNEFISIFLASVALTVLFDAPFQNLKKLLI--KRPTA--AKVVK----DSKAKAAES 801
             ..:|....|.|..:.:|.:|||..|:.||:  |||.|  |.||:    :.||...||
  Fly   639 FWTDFGFTILFSYLMHILIEAPFAGLESLLLPAKRPNAKPAAVVEPRMSEVKASVEES 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drd	NP_001033845.1	NRF	154..292	CDD:466307	37/140 (26%)
		OafA	377..788	CDD:441440	117/435 (27%)
CG14219	NP_608322.1	NRF	101..211	CDD:214781	39/152 (26%)
		OafA	284..676	CDD:441440	113/422 (27%)