DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment drd and CG33337

DIOPT Version :9

Sequence 1:	NP_001033845.1	Gene:	drd / 318102	FlyBaseID:	FBgn0260006	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_996269.2	Gene:	CG33337 / 2768678	FlyBaseID:	FBgn0053337	Length:	708	Species:	Drosophila melanogaster

Alignment Length:	731	Identity:	184/731 - (25%)
Similarity:	307/731 - (41%)	Gaps:	116/731 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 DDDDQVEEDERA------------YLYNIGKRFLAITQPFDAARNPDASTLCRRQMHQFLNALDN 167
            :|...:||.:|.            |..|:....|::   ||:.....|..||...:.:.::||..
  Fly    22 EDRSVLEEYQRLRKLKPLGIEFADYFQNVTLNDLSL---FDSRLPTQADLLCLNDLTKLVSALQG 83

  Fly   168 FDLWALKMHDSSGKLNSGILNGNINQPGDFDQCLGIQQRMNQDQDAGQDQDGDSIIRGQYCLAYA 232
            ...||.||.|:.|.:.|||..||:...|:||:|:.|::              || |||:||....
  Fly    84 GQYWAFKMIDAWGGIPSGIFTGNVYDLGNFDECINIKK--------------DS-IRGKYCFLDV 133

  Fly   233 QP--VLPHNSKRLKSFFKLIQSHGPFKSEFNDPGHRVPRYSLINWGLCVPSGCSA----RDVEYS 291
            .|  :|...|. |....|                        |....|.|:.|||    :.|:..
  Fly   134 SPAKILGVESS-LAGILK------------------------IKTATCFPASCSATHMNKFVDTI 173

  Fly   292 VAEYLGNQTASTGITFNVRVEPQMCQVRDQRPWDRNTTWAVRFFLLVLSVAVLSTIYDR-STKSQ 355
            :...|.....||.::    :....||..:..||...|...:....|:..:..::|:||. ..|||
  Fly   174 LKRILNVSIPSTAMS----ISDDSCQTAESEPWSGLTILTIVILSLMGVIVAIATLYDYFLVKSQ 234

  Fly   356 PKQNPWFTAFSLDKNLRWLFS---TSSAPGDIEAVHGIRFLNAIMLIFSHKSMAMFFNPYNNRTA 417
            .:.:.....||...|...||.   ..|.|..||.:||||.::...:::.|:...:|..|..||..
  Fly   235 DQLHTAVKLFSARANSCALFRIVVNQSNPNVIECLHGIRCMSLFWVVWIHQYDNVFSAPNINRFR 299

  Fly   418 MSESLGQPWTVIGRAASLYTDPFLLFSGMLTSYSLFGRLMKQQ-PIRLKNEYISRLMRIVPPLAA 481
            ....|..|:|:.....:...|.|....|.|.|.:..|.:.|.. .|.:...||.|.:||.|.||.
  Fly   300 FLSWLQTPFTMFFLEGNFSVDSFFFIGGFLVSLNALGTMEKNNGKINVPRMYIRRFIRIFPILAM 364

  Fly   482 LILFCTYVLPLWGSGPQWNLVVGHHAD--ICKKNWWRNLLFIHNYFGFSEMCLTHTHHLGIDTEL 544
            .||..|.:..:.|.||   |..|.::.  .|.|.|:..|||:.|:  .::|||.||.:|.:|.:|
  Fly   365 SILVYTQLTGVLGDGP---LFKGGYSKKASCAKTWYMTLLFVVNF--ANDMCLDHTWYLAVDMQL 424

  Fly   545 FAVAPLLILALWRWPRRGLFALLLLCTVGTAARYYTTIVNQLSNYIYFGTNIQRL-FRTADYMYS 608
            |.::|:|:.||::|.::...|:.:|..:.:...:.|.:||..|        |:.| |......|.
  Fly   425 FLISPILLFALYKWGKKAAAAIGVLIVLLSGCLFATMMVNHYS--------IKSLDFSLQKKTYF 481

  Fly   609 FPPHRSTVYIMGILLGY--VLRKYQNARLSSLQLRLGWLVATVCVLASLLGPAPMGDIN--YVYN 669
            :....:..:::|.|.||  .|.|.:..:::.:.:..||::....:..|:....|..:..  ::..
  Fly   482 YTHTHAAPWLIGFLYGYFVFLNKGRKFKMNWIAVWSGWILCLAMLFTSIFALYPKLESGKPWLMT 546

  Fly   670 STHAAIYAAFAPIAWCLFFSWIVFVSHNGYTNKLTKLFAWRGFQVSTKLSYAIYLTQFPVFFFNV 734
            :...:.|.....:.|.:...|:||....||........:...:|..:||||:||:  :..|...:
  Fly   547 TLEVSSYYTLTRVGWPMAVGWVVFACMQGYGGMANTFLSSPLWQPISKLSYSIYI--WHSFIQEI 609

  Fly   735 GRRRHIHHYYNFVSIILDTNEFIS------IFLASVALTVLFDAPFQNLKKLLIKRPTAA--KVV 791
            .:|            |:.||.:.|      .|.:::..|||    |..|..|||:.|...  :::
  Fly   610 NKR------------IVRTNTYFSNYQVMLNFWSTMGFTVL----FSYLLYLLIEAPIGGLDRLL 658

  Fly   792 KDSKAKAAESQDATTT 807
            :..|...||::..|.:
  Fly   659 RPKKKAPAENKPMTNS 674

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drd	NP_001033845.1	NRF	169..>289	CDD:214781	34/125 (27%)
		OafA	371..791	CDD:224748	113/438 (26%)
		Acyl_transf_3	384..770	CDD:280013	102/399 (26%)
CG33337	NP_996269.2	NRF	85..196	CDD:214781	39/154 (25%)
		Acyl_transf_3	266..645	CDD:280013	105/409 (26%)
		OafA	300..666	CDD:224748	99/396 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25504
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920