DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment drd and CG30471

DIOPT Version :9

Sequence 1:	NP_001033845.1	Gene:	drd / 318102	FlyBaseID:	FBgn0260006	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_001261001.1	Gene:	CG30471 / 246633	FlyBaseID:	FBgn0050471	Length:	735	Species:	Drosophila melanogaster

Alignment Length:	761	Identity:	168/761 - (22%)
Similarity:	297/761 - (39%)	Gaps:	194/761 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 GKRFLAITQPFD--------------AARNPDASTLCRRQMHQFLNALDNFDLWALKMHDSSGKL 182
            ||...||..|.:              .|...:.:..|...:.|....:.:...||:|:.|:||..
  Fly    54 GKEAAAIESPHEPHLTRSSVIFGLTKVANESNVTPSCYAHLKQVQRGILSRQPWAMKVLDASGTK 118

  Fly   183 NSGILNGNINQPGDFDQCLGIQQRMNQDQDAGQDQDGDSIIRGQYCLAYAQPV---LPHNSKRLK 244
            .||.:.|.....|..|.|.|::                            :||   |..|.:|:.
  Fly   119 PSGFVFGQNYWLGSRDGCEGVR----------------------------RPVGITLSRNYERVM 155

  Fly   245 SFFKLIQSHGPFKSEFN--DPGHRVP--------RYSLINWGLCVPSGCSARDVEYSVAEYLGNQ 299
            .:..|.|| .||..::.  ...||.|        ...:::.|||:||.||:.:|:.....|:...
  Fly   156 HYSILTQS-APFGMDYRVIYMRHRSPWQVEIKVMSEQVLHIGLCLPSSCSSEEVKQLARYYVAGD 219

  Fly   300 TASTGITFNVRVEPQMCQVRD----QRPWDRNTTWAVRFFLLVLSVAVLSTI------------- 347
            ..:....|:::  |::..::|    :|.:.|.|     |.|:|.::.|...:
  Fly   220 LFAADDMFDMK--PEVLYMKDLRLSERFYQRLT-----FRLVVAAILVTGALMLCAQQVRVAKRA 277

  Fly   348 -----------------YDRSTKSQPKQNPWFTAFSLDKNLRWLFS-TSSAPGDIEAVHGIRFLN 394
                             .|...|.||.|: :.:.|.:..|.|.:.: ..:.||:|..::|:|.:.
  Fly   278 DEPDLGLAPVESELWQALDTLLKWQPFQS-FVSCFDVANNWRKISAMRENQPGEIPIMNGLRSVC 341

  Fly   395 AIMLIFSHKSMAMFFNPYNNRTAMSESLGQPWTVIGRAASLYTDPFLLFSGMLTSYS-------- 451
            ||.::..|....|:|. .:|:|.:.....|.:......|.|..|.|...||.|.:|:
  Fly   342 AIWILIFHVVWYMYFT-VHNKTVLISYAEQVFFQYVSTAPLLVDVFFTISGFLQTYNFLRNEQQL 405

  Fly   452 -------------LFGRLMKQQPIRLKNEYISRLMRIVPPLAALILFCTYVLPLWGSGPQWNLVV 503
                         |||:|:..:.:||...|:     :|  :.::.|...|:         .::.|
  Fly   406 DAVRRNGLWGNVKLFGKLLFHRYLRLGPLYL-----VV--MGSVDLAFAYI---------GDVSV 454

  Fly   504 GH----HADICKKNWWRNLLFIHNYFGFSEMCLTHTHHLGIDTELFAVAPLLILALWRWPRRGLF 564
            .|    ..::|.::||||||||.|.|...|||...:..|..|.:.|.:|. ::|.::....:...
  Fly   455 FHINERFDELCPQHWWRNLLFIQNLFDHREMCANWSWSLACDMQFFLLAN-IVLFIYAKHEKLAK 518

  Fly   565 ALLLLCTVGTAARYYTTIVNQLSNYIYFGTNIQRLFRTADYMYSFPPHRSTVYIMGILLG--YVL 627
            |:.|...:||....|...:.:...:.:..|     :.|...:|:.|..|...||:|.:..  |..
  Fly   519 AITLTGLMGTITWSYGIGIAKKFEFSFDST-----YATGTQIYTSPFVRVLPYIVGAIAAWYYQE 578

  Fly   628 RKYQNARLS----------SLQLRLGWLVATVCVLASLLGPAPMGDINYVYNSTHAAIYAAFAPI 682
            :::|.:.||          ||::.:|.:.:||           ..|:.|:...:...:..|...:
  Fly   579 QRFQVSELSERRICRWWHFSLKVFVGCIYSTV-----------KRDLGYLITISLFVLGRALFSL 632

  Fly   683 AWCLFFSWIVFVSHNGYTNKLTKLFAWRGFQVSTKLSYAIYLTQFPVFFFNVGRRRHIHHYYNFV 747
            ..|    |::..|.:|.....::|...:.||...:|||||||.. |:....|         |:..
  Fly   633 TIC----WMIVGSASGTGVWWSRLLEAKFFQHLNRLSYAIYLLN-PLVIALV---------YSLT 683

  Fly   748 SIILDTNEFI----------SIFLASVALTVLFDAPFQNLKKLLIK 783
            |.....:.|:          .::|||:|.::.|:.|:.||..||:|
  Fly   684 STSSAVDPFLLSVICCGFTMIVYLASIAFSLAFELPYSNLSSLLLK 729

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drd	NP_001033845.1	NRF	169..>289	CDD:214781	33/132 (25%)
		OafA	371..791	CDD:224748	108/461 (23%)
		Acyl_transf_3	384..770	CDD:280013	98/432 (23%)
CG30471	NP_001261001.1	NRF	105..230	CDD:214781	36/153 (24%)
		OafA	321..719	CDD:224748	101/445 (23%)
		Acyl_transf_3	331..709	CDD:280013	95/425 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920