DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment drd and oac-7

DIOPT Version :9

Sequence 1:	NP_001033845.1	Gene:	drd / 318102	FlyBaseID:	FBgn0260006	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_507120.3	Gene:	oac-7 / 180096	WormBaseID:	WBGene00007835	Length:	702	Species:	Caenorhabditis elegans

Alignment Length:	726	Identity:	170/726 - (23%)
Similarity:	292/726 - (40%)	Gaps:	173/726 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 STLCRRQMHQFLNALDNFDLWALKMHDSSGKL-NSGILNGNINQPGDFDQCLGIQQRMNQDQDAG 214
            |..|.::..|.:.  |||  :|::..|:.||| :|||....:...|.:.:|    ||:     :|
Worm    69 SRKCNKKEIQIIK--DNF--YAIEQLDAFGKLPSSGIFEVPLIFDGSYQEC----QRI-----SG 120

  Fly   215 QDQDGDSIIRGQYCLAYAQPVLPHNSKRLKSFFKLIQSHGPFKSEFNDPGHRVPRYSLINWGLCV 279
            :..:.:      ||  |...|...||                .......|..:|..:......|:
Worm   121 KKYETN------YC--YLVLVPGRNS----------------SCSIGGGGGFLPSAAFFRSATCM 161

  Fly   280 PSGCSARDVEYSVAEYLGNQ------TASTGITFNVRVEPQMCQVRDQRPWDRNTTWAVRFFLLV 338
            ...|::.|:     ..|.||      ||......:..||      :|...|..:.     |..::
Worm   162 SVSCTSEDL-----PQLFNQLPLMPFTACAAFCSSFPVE------KDSAFWGFSA-----FMCVM 210

  Fly   339 LSVAVLSTIYD------RSTKSQPKQ----NPWFTAFSLDKNLRWLFST-SSAPGDIEAVHGIRF 392
            :|:.||:|..|      ::..|.|.|    ......|||..|...|.|. ...||.|:.:..|||
Worm   211 ISILVLATFIDYLKDAMKNEHSPPPQPNLIMKMLLTFSLWTNAGVLLSVKEQKPGFIKCLDCIRF 275

  Fly   393 LNAIMLIFSHKSMAMFFNPYNNRTAMSESLGQPWTVIGRAASLYTDPFLLFSGMLTSYSLFGRLM 457
            |:.:.::..|  ...|..|.:...:||......|..:...|.:..|.|.|.||::.:|..|.:
Worm   276 LSMLWVVTGH--TFTFVIPPDTLLSMSHFTDHFWNHLLLNAFVSVDTFFLLSGIVVAYLFFKQ-- 336

  Fly   458 KQQPIRLKNE------YISRLMRIVPP----LAALILFCTYVLPLWGSGP----QWNLVVGHHAD 508
            |.:..::|:.      |:.|.:|:.||    :...|::..||     .||    |:|.::...|
Worm   337 KHKSSQIKSPLTWIIFYMHRYLRLTPPYMIFIGFYIVYGKYV-----QGPFSASQFNTLLSSIA- 395

  Fly   509 ICKKNWWRNLLFIHNYFGFSEMCLTHTHHLGIDTELFAVAPLLILALWRWPRRGLFALLLLCTVG 573
            .|:..||:||.:|:|....|..|...:.:|.:||:|:..||::::.|
Worm   396 TCESYWWKNLFYINNMGDSSTACYAPSWYLAVDTQLYIFAPIILVGL------------------ 442

  Fly   574 TAARYYTTIVNQ-----------LSNYI----------YFGT-NIQRLFRTADYMYSFPPHRSTV 616
                ||:.|:..           ::.||          :||. |...|:   |.:|..|..|...
Worm   443 ----YYSAIIGSSLIAVGMIGSLVTVYILYSIYDLPADFFGNGNTNLLY---DMIYHKPWIRCPP 500

  Fly   617 YIMGILLGYVLRKYQNARLSSLQLRLGWLVATVCVLASL-LGPAPM-GDINY---VYNSTHA-AI 675
            |::|:|:||.|     |.....::|:.|.:|.:..|.:. ||.|.| ...:|   .|.|..| |.
Worm   501 YLIGLLIGYGL-----AVFGQRKIRIHWFLAVIGWLVAFGLGMACMFSTYDYDKGAYWSIFARAT 560

  Fly   676 YAAFAPIAWCLFFSWIVFVSHNGYTNKLTKLFAWRGFQVSTKLSYAIYLTQFPVFFFNVGRRRHI 740
            |..|:.|||.:..||::..:|.|:...:....:...:|...:|||..|:..|...|:.:......
Worm   561 YYNFSRIAWSIAVSWVIVANHMGWGGPIDAFMSHPMWQPLGRLSYCAYIVHFFTLFWYLNINDSS 625

  Fly   741 HHYYNFVSIILDTNEFISI------FLASVALTVLFDAPFQNLKKLLI-------KRPTAAKV-- 790
            .|:|:...:.:    :.::      ::.:...:.||:.|...|||::|       :|....:|
Worm   626 MHFYSTFQVFI----YYAVPACLLSYIFAFFWSSLFEIPILKLKKMMIEAILQRNQRSELTQVET 686

  Fly   791 -VKDSKAKAAE 800
             |::|.|.:.|
Worm   687 LVQESNAGSEE 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drd	NP_001033845.1	NRF	169..>289	CDD:214781	24/120 (20%)
		OafA	371..791	CDD:224748	114/478 (24%)
		Acyl_transf_3	384..770	CDD:280013	101/433 (23%)
oac-7	NP_507120.3	NRF	83..191	CDD:214781	31/147 (21%)
oac-7	NP_507120.3	OafA	261..666	CDD:224748	107/448 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820