DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment drd and oac-31

DIOPT Version :9

Sequence 1:	NP_001033845.1	Gene:	drd / 318102	FlyBaseID:	FBgn0260006	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_503441.2	Gene:	oac-31 / 178643	WormBaseID:	WBGene00018707	Length:	705	Species:	Caenorhabditis elegans

Alignment Length:	774	Identity:	179/774 - (23%)
Similarity:	295/774 - (38%)	Gaps:	195/774 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 FDAARNPDASTLCRRQMHQFLNALDNF-----------------------DLWALKMHDSSGKL- 182
            ||.....|.|..|......:|.:|:.|                       :|:|:|..|:.|:.
Worm    30 FDPKPLHDLSEKCLNDTDTWLKSLEIFSTVSVECLTLNNCTTQESKILDENLYAVKQLDAFGEFP 94

  Fly   183 NSGILNGNINQPGDFDQCLGIQQRMNQDQDAGQDQDGDSIIRGQYCLAYAQPVLPHNSKRLKSFF 247
            ..|:|.......|.:.:|..|              ||:. .:..||..            :.:|.
Worm    95 TPGLLELRTLYDGSYQECDRI--------------DGER-YKTNYCYL------------ILNFG 132

  Fly   248 KLIQSHGPFKSEFNDPGHRVPRYSLINWGLCVPSGCSARDV----------EYSVAE-YLGNQTA 301
            |.|....|  |.:::...|:        .:|:|..||.:|:          .::..: |....|.
Worm   133 KNISCSAP--SVYSNVTLRM--------AVCLPDSCSHQDMINIFNQLSPYPFTACDAYCVKNTV 187

  Fly   302 STGITFNVRVEPQMCQVRDQRPWDRNTTWAVRFFL-LVLSVAVLSTIYDRSTK-----SQPKQNP 360
            ...:.|                      |....|| :|::||:.:|:.|....     |..|:..
Worm   188 EKDVPF----------------------WGFTVFLTIVIAVAIFATLLDYVQDAVLGLSNLKEKN 230

  Fly   361 WF----TAFSLDKNLRWLFSTSS-APGDIEAVHGIRFLNAIMLIFSHKSMAMFFNPYNNRTAMSE 420
            .|    ..|||..|...:.|... .||.|:::..||.|:...:|..|.  .::....:....:.|
Worm   231 IFIKIILTFSLWTNAELILSVKEHKPGFIKSLDCIRGLSIFWVITGHS--FIYMTQADTMKPVME 293

  Fly   421 SLGQPWTVIGRAASLYTDPFLLFSGMLTSYSLFGRL-----MKQQPIRLKNEYISRLMRIVPPLA 480
            ...|.|..:...|.:..|.|...||::.:| ||.::     |...|:.....|:.|.:|:.|.:.
Worm   294 FQNQFWNHLIINAPVSVDSFFALSGIVVAY-LFFKMKPNIKMAASPVTWILFYVHRYLRLTPTVM 357

  Fly   481 ALILFCTYVLPLWGSGP---QWNLVVGHHADICKKNWWRNLLFIHNYFGFS----EMCLTHTHHL 538
            ..|.|.|...| :..||   .::.|.....:.||..||.|||:|:|:....    ..|...|.:|
Worm   358 IFIGFFTVYFP-YVQGPFAASFSNVQFPQVEACKDYWWHNLLYINNFDNSQHRERNTCYAITWYL 421

  Fly   539 GIDTELFAVAPLLILALWRWPRRGLFALLLLCTVGTAARYYTTIVNQLSNYIYF----------G 593
            .:||:|:.:||::::||:       |:.    .||||......:.:.::.||.|          |
Worm   422 AVDTQLYILAPIVLIALF-------FSF----AVGTAIIVAGCVGSIIATYILFDLYDVPADPLG 475

  Fly   594 TNIQRLFRTADYMYSFPPHRSTVYIMGILLGYVLRKYQNARLSSLQLRLGW-----------LVA 647
            ....|.|  ....||.|..|...|::|:|.||:|..|...|     :||.|           :||
Worm   476 NGDHRYF--FGIGYSKPWIRCPPYLVGLLTGYLLATYGTRR-----IRLNWAVSIGVWIVAFVVA 533

  Fly   648 TVCVLASLLGPAPMGDINYVYN-----STHA-AIYAAFAPIAWCLFFSWIVFVSHNGYTNKLTKL 706
            ..|:.::           |.|:     ||.: |.:..|..:.|.:|..|:|..:|.|:...:...
Worm   534 GFCIFST-----------YDYDKGEQWSTFSRATFFNFHRLGWGVFVCWVVGANHMGWGGPIDTF 587

  Fly   707 FAWRGFQVSTKLSYAIYLTQFPV--FFFNVGRRRH---IHHYYNFVSIILDTNEFISIFLASVAL 766
            .:...:|...:|||..|:..:.|  |:.|||...|   ..|.:.::||......|:..|..|
Worm   588 MSHPIWQPFGRLSYCAYIVHWMVLYFYLNVGGALHYTSAWHVFLYISIPATVLSFVFAFFWS--- 649

  Fly   767 TVLFDAPFQNLKKLLIKRPTAAKVVKDSK---AKAAESQDATTTTLAS-QPSSTALLQS 821
             .||:.|...|:|:||:     .:|..|:   ||.:..:..|..|.|| :...|..:||
Worm   650 -CLFEMPILKLEKMLIE-----SLVGRSQMPPAKTSLKEKITEETEASYEDMETGKIQS 702

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drd	NP_001033845.1	NRF	169..>289	CDD:214781	25/130 (19%)
		OafA	371..791	CDD:224748	117/464 (25%)
		Acyl_transf_3	384..770	CDD:280013	107/429 (25%)
oac-31	NP_503441.2	NRF	80..184	CDD:214781	26/140 (19%)
oac-31	NP_503441.2	OafA	253..659	CDD:224748	112/442 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820