DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment drd and rhy-1

DIOPT Version :9

Sequence 1:	NP_001033845.1	Gene:	drd / 318102	FlyBaseID:	FBgn0260006	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_495954.1	Gene:	rhy-1 / 174455	WormBaseID:	WBGene00012324	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	488	Identity:	98/488 - (20%)
Similarity:	204/488 - (41%)	Gaps:	102/488 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   339 LSVAVLSTIYDRSTKSQPKQNPWFTAFSLDKNLRWLFSTSSAPGDIEAVHGIRFLNAIMLIFSH- 402
            :::.|:.|:...|.         |:..||.::::.|.:..|:..|:..:  .||:..:.::.:|
Worm    58 MTLVVIGTLAPVSV---------FSCLSLKRSVKELLTERSSKLDVLDI--FRFVAILWVMLNHT 111

  Fly   403 ------------KSMAMFFNPYNNRTAMSESLGQPWTVIGRAASLYTDPFLLFSGMLTSYSLFGR 455
                        .|...|.:..::.......:|.        ::|..:.||:.||:|.:.|...:
Worm   112 GSEGRIDILDRLPSADAFKSAMHDHPIFGALMGN--------SALGVEIFLVLSGLLAARSWLRK 168

  Fly   456 LMKQQPI--RLKNEYISRLMRIVPPLAALILFCTYVLPLWGSGPQWNLVVGHHAD--ICKKNWW- 515
              ..:|.  ..|:....||:|:.|   ::.:| .|:    .:||..|.::..::.  :....:|
Worm   169 --ADEPFFQHWKSFIARRLLRLAP---SMFIF-VYI----AAGPIMNALLPRYSSSMVSACGFWG 223

  Fly   516 --RNLLFIHNYFGFSEMCLTHTHHLGIDTELFAVAPLLILALWRWPRRGLFALL--LLCTVGTAA 576
              .::.|..|:.. :..|:.:..:||:|.:|:.|||:.:..|.::|:||:...:  ::.::...|
Worm   224 ILSHVTFTSNWQS-TPTCMGYLWYLGLDMQLYMVAPIFLNLLHKFPKRGMALTITTIIASMVIRA 287

  Fly   577 RYYTT--IVNQLSNYIYF-------GTNIQRLFRTADYMYSFPPHRSTVYIMGILLGY--VLRKY 630
            .|.|.  ..||....|.|       ...::.::.....|||.|..:...:::|:||||  |..||
Worm   288 GYCTAYGTCNQSDVDIPFISYPGQDAETLKSIYAGLWDMYSRPYTKCGPFLIGLLLGYITVSSKY 352

  Fly   631 QNARLSSLQLRLGWLVATVCVLASLL--------GPAPMGDINYVYNSTHAAIYAAFAPIAWCLF 687
            .....:|..|....|:..:..:.::|        |       |.:||:.:.|::.:...:|....
Worm   353 IMVSTTSKTLFRSSLIVAIATIYAILPEYWNPNAG-------NTLYNTVYTAVFRSVFAMAISGM 410

  Fly   688 FSWIVFVSHNGYTNKLTKLFAWRGFQVSTKLSYAIYLTQFPVFFFNVGRRRHIHHYYNFVSI--- 749
            .:.:.|......||.:        |.:..||:|..||...||.:        |.::..|:..
Worm   411 IAALYFRQEYRPTNPI--------FAMLAKLTYNAYLLHMPVVY--------IFNWLPFLQAATS 459

  Fly   750 ---ILDTNEFISI--FLASVALTVLFDAPFQNL 777
               :|....|::|  |:|::...:..:||..:|
Worm   460 PIHLLLVLPFVAILSFIAALIFYLFIEAPIGHL 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drd	NP_001033845.1	NRF	169..>289	CDD:214781
		OafA	371..791	CDD:224748	92/456 (20%)
		Acyl_transf_3	384..770	CDD:280013	86/434 (20%)
rhy-1	NP_495954.1	OafA	89..489	CDD:224748	89/443 (20%)
rhy-1	NP_495954.1	Acyl_transf_3	95..479	CDD:280013	86/427 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780