Protein Alignment drd and oac-46

DIOPT Version :10

• Sequence 1: NP_001033845.1
• Gene: drd / 318102
• FlyBaseID: FBgn0260006
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_495886.2
• Gene: oac-46 / 174415
• WormBaseID: WBGene00011768
• Length: 676
• Species: Caenorhabditis elegans
• Alignment Length: 790
• Identity: 163/790 - (20%)
• Similarity: 289/790 - (36%)
• Gaps: 254/790 - (32%)

  Fly   138 ITQPFDAARNPDASTLCRRQM---HQFLNALDN--------FDLWALKMHDSSGKLNSGILNGNI 191
            |.|..:.::..|.|..|::.:   :.:||.::.        |:.:|
 Worm    27 ILQFINRSQTLDLSLKCKQSLALVYDYLNDIETLTDQKICYFESFA------------------- 72

  Fly   192 NQPGDFDQCLGIQQRMNQDQDAGQDQDGDSIIRGQYCLAYAQPVLPHNSKRLKSFFKLIQSHGPF 256
            ..|.|.        .:::|||..       :.:|..||..|...:...|:....:   ..:|.
 Worm    73 TGPNDL--------FLSRDQDRW-------VYKGYECLLSAGETVYSKSEHPMHY---CYTHD-- 117

  Fly   257 KSEFNDPGHRVPRYSLINWGLCVPSGCSARDVEYSVAE---YLGNQTASTGITFNVRVEPQMC-Q 317
                :|...|||.:|     :|:||.|:  |....:.|   .:.:..|:..|||..      | :
 Worm   118 ----DDKDKRVPAFS-----VCIPSPCA--DENQKLLEEWRRITHPEATEPITFTA------CTR 165

  Fly   318 VRDQRPWDRNTTWAVRFFLLVLSVA------------VLSTIYDRSTKSQPKQNPW----FTAFS 366
            .|.::.|          |.|.:.:|            |::||:........|.  |    ..|||
 Worm   166 SRHEKQW----------FELPVPIADFGFNMSLAMLVVMATIFHNMRGEDAKS--WSARILLAFS 218

  Fly   367 LDKNLRWLFSTSSAPGD-IEAVHGIRFLNAIMLIFSHKSM---AMFFNPYNNRTAMSESLGQPWT 427
            ...||:.|.:....|.. |..:.|:||.:.:..:..|..:   |...|..:.:.:|.::....|.
 Worm   219 AKTNLKKLIALPKDPQSCITCLLGLRFGSMVWTLIGHSFIFVQAYMENVEDFKNSMVDNFFNQWI 283

  Fly   428 VIGRAASLYTDPFLLFSGMLTSYSLFGRLMK----QQP----------------IRLKNEYISRL 472
            .   ..:|..|.||...|.:.|||.|.:.:|    ::|                :||...|:..|
 Worm   284 T---NFTLSVDVFLTLGGTVLSYSWFRKWLKNTSEEEPTWTSWGYWLKFYRHRVVRLYPAYLYTL 345

  Fly   473 MRIVPPLAALILFCTYVLPLWGSGPQWNLVVGHHADICKKNWWRNLLFIHNYFGFSEMCLTHTHH 537
            :.:     .|.:..|:..|:|   |..:..:.     |.|.||:|:||:::.  ....|:..|.:
 Worm   346 LAV-----TLRISVTHFHPMW---PPTDPAIQ-----CPKYWWQNVLFVNSI--LDNQCMPWTWY 395

  Fly   538 LGIDTELFAVAPLLILALWRWPRRGLFALLLLCTVGTAARYYTTIVNQLSNYIYF--GTNIQRLF 600
            :|.:...:.::|:.:|.|.:.|:.|    .:||.|                .|.|  |.|::.:.
 Worm   396 IGTEFIYYLLSPIFLLTLRKAPKIG----FILCFV----------------VIMFSAGLNVESIV 440

  Fly   601 RTADYMYSFPP---------------------------HRSTVYIMGILLGYVLRKYQ------- 631
            |.     :|||                           :|...|::||||||.|.:||
 Worm   441 RN-----NFPPTQFLWKQPEMFNPNFIQHHLELYIKPQYRIGPYLIGILLGYQLARYQRIPVKPQ 500

  Fly   632 --NARLSSLQLRLGWLVATVCVLASLLG--PAPMGDINYVYNSTHAAIYAAFAPIAWCLFFSWIV 692
              |..:.|:     |.||.|.:|..|.|  ||..|..:..:.:.| .:|.|.....:.:..::::
 Worm   501 QSNKYIISM-----WSVALVGILFGLYGLYPALQGWDSIAWRAYH-LLYGALHRDIFSIGIAFLI 559

  Fly   693 FVSHNGYTNKLTKLFAWRGFQVSTKLSYAIY------------LTQFPVFFFNVGRRRHIHHYYN 745
            ::.|.|....:....:...|.....||::.|            |..||: :||......||   .
 Worm   560 YICHTGIGGPVNVFLSSNFFLPLANLSFSAYLFHMIPVVLTYMLVPFPI-YFNTQIPLFIH---C 620

  Fly   746 FVSIILDTNEFISIFLASVALTVLFDAPFQNLKKLLIKRPTAAKVVKDSKAKAAESQDATTTTLA 810
            ||.::      |:.|.| :..|::.:.|..|:::||:..|                   ..|||.
 Worm   621 FVQLL------ITYFFA-IICTMVSELPALNIERLLLASP-------------------PKTTLK 659

  Fly   811 SQPSSTALLQ 820
            ..|.:.:.:|
 Worm   660 PSPPTDSEIQ 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drd	NP_001033845.1	NRF	154..292	CDD:466307	26/148 (18%)
		OafA	377..788	CDD:441440	106/486 (22%)
oac-46	NP_495886.2	OafA	242..653	CDD:441440	103/470 (22%)