DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment drd and oac-9

DIOPT Version :9

Sequence 1:	NP_001033845.1	Gene:	drd / 318102	FlyBaseID:	FBgn0260006	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_491809.2	Gene:	oac-9 / 172323	WormBaseID:	WBGene00016753	Length:	820	Species:	Caenorhabditis elegans

Alignment Length:	746	Identity:	151/746 - (20%)
Similarity:	264/746 - (35%)	Gaps:	213/746 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 WALKMHDSSGKLNSGI-LNGNINQPGDFDQC---LGIQQRMNQDQDAGQDQDGDSIIRGQYCLAY 231
            ||:::.||......|: ..|.....|||:.|   ..::.|                 :..||
Worm    88 WAVRLIDSLPTKPPGLSRKGPFFFIGDFETCKELWSVEHR-----------------QVHYC--- 132

  Fly   232 AQPVLPHNSKRLKSFFKLIQSHGPFKSEFNDPGHRVPRYSLINWGLCVPSGCSARDVEYSV---A 293
                      .||...||.....|                 :..|:|:||.|....:...:   .
Worm   133 ----------TLKGTVKLGSETLP-----------------VTTGVCLPSNCHENQMSKLLNLAK 170

  Fly   294 EYLGNQTASTGITFNVRVEPQMCQVRDQRPWDRNTTWAVR---------FFLLVLSVAVL----- 344
            |||.|:|        :.|:...|.      ...::||:|:         |.|.:|::..|
Worm   171 EYLFNET--------IHVDSVYCS------HGTDSTWSVKKPFVLFSLFFILALLTIGTLTEKMN 221

  Fly   345 ---------------------------------------STIYDRSTKSQPKQ-------NPWF- 362
                                                   |..:|.|.:|:..:       |..|
Worm   222 RDGLIKKSNTKMRRMIHKKSFDVTRSSAVSISEDRSDRESCGFDSSGESEDNESLANSSVNRQFA 286

  Fly   363 ------------------------TAFSLDKNLRWLFSTSSAPGDIEAVHGIRFLNAIMLIFSHK 403
                                    :|||:..:|.:||..|:.  |::.|:..|..::..:||||.
Worm   287 PSIALTYRTLATISLSNSLLVNILSAFSVRSSLTYLFRNSTR--DVKLVNLFRVCSSFWVIFSHT 349

  Fly   404 SM-AMFFNPYNNRTAMSESLGQPWTVIGRAASLYTDPFLLFSGMLTSYSLFGRLMKQQPIRLKNE 467
            .: ::.|.......|........|......:||..|.||..|..:.|||:..:::    .|..:.
Worm   350 CLFSLHFTDTIRSVARKGESVVGWRNFMMNSSLAVDTFLFLSACVASYSIRKKIL----FRGSSS 410

  Fly   468 YIS----------RLMRIVPPLAALILFCTYVLPLWGSGPQWNL--VVGHHADICKKNWWRNLLF 520
            ..|          |.:|::|.|:..:||...|......||.||.  :.|...::  ...|.:..|
Worm   411 NFSIIKCLALLGHRCLRLLPALSLYLLFMGLVYNHLADGPFWNANGMFGTECNV--TTIWPHFAF 473

  Fly   521 IHNYFGFSEMCLTHTHHLGIDTELFAVAPLLILALWRWPRRGLFALLLLCTVGTAAR-----YYT 580
            :.|:  |...|:....::.:|.:|:...|::|..|.:: |.|....::||.:....|     .||
Worm   474 VSNF--FPSTCVPWLWYISLDFQLYLTLPIVIFFLSKF-RFGFTFAIVLCILALVYRSLMYAIYT 535

  Fly   581 TIVNQLSNYIYFGTNIQRLFRTAD----YMYSFPPHRSTVYIMGILLG-YVLRKYQNARLSSLQL 640
            ...|.      |...:...|..|:    .:|:.|..|...:.:|||.| |:.:......|.|: .
Worm   536 LPANM------FVEMLSGKFEKAELSFKLLYTSPLSRCPPFFLGILTGWYICQIRYLGTLRSI-T 593

  Fly   641 RLGWLVATVCVLA-SLLGPAPMGDINYVYNSTHAAIYAAFAPIAWCLFFSWIVFVSHNGYTNKLT 704
            ..|..:..|.:|| :|.||       :.|:......:|....|.|....:.:|.::.|||...:.
Worm   594 SFGLKILAVSLLAFALFGP-------FFYSEFLTYPHAISNRILWASGLAILVVLAQNGYNFGVF 651

  Fly   705 KLFAWRGFQVSTKLSYAIYLTQFPVFFFNVGRRRH-----IHHYYNFVSIILDTNEFISIFLASV 764
            |:|..:...|.::||:.:||:..|:..:.:...|.     ...|:.|::|.:.....:..|..::
Worm   652 KVFGGQTLVVLSRLSFGVYLSHEPILLYYLNSLRQPMSPTSFGYFMFITISIYVLSLVCAFFIAI 716

  Fly   765 ALTVLFDAPFQNL--KKLLIKRPTAAKVVKD 793
            ::.|    |..||  |.|:..|......:||
Worm   717 SIEV----PLLNLERKLLMTTRNMKEDTMKD 743

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drd	NP_001033845.1	NRF	169..>289	CDD:214781	23/121 (19%)
		OafA	371..791	CDD:224748	103/450 (23%)
		Acyl_transf_3	384..770	CDD:280013	92/414 (22%)
oac-9	NP_491809.2	NRF	88..187	CDD:214781	30/159 (19%)
oac-9	NP_491809.2	Acyl_transf_3	333..715	CDD:376607	91/404 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920