DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32581 and THI21

DIOPT Version :9

Sequence 1:	NP_001096988.2	Gene:	CG32581 / 318098	FlyBaseID:	FBgn0052581	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_015065.1	Gene:	THI21 / 855870	SGDID:	S000006179	Length:	551	Species:	Saccharomyces cerevisiae

Alignment Length:	245	Identity:	50/245 - (20%)
Similarity:	80/245 - (32%)	Gaps:	91/245 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PKSVSTAELPSTSTGASSSSSTLSNNVSYDKIAWTRDITEP--------LAEESSTSQLRPL--- 57
            ||.|....|.:|| |:|.:...:::.:: :|||...||..|        |.|:...|:||.:
Yeast   121 PKLVVDPVLVATS-GSSLAGKDIASLIT-EKIAPFADILTPNIPECFKLLGEDREISKLRDIFEV 183

  Fly    58 ----------------GTSIPTNSTASELKKS------------------NTSYSF-TGDYLSGG 87
                            |..||.|....:....                  ||:::. ||..|:..
Yeast   184 AKDLAKITKCSNILVKGGHIPWNDEEGKYITDVLYLGAEQRFITFKGNFVNTTHTHGTGCTLASA 248

  Fly    88 NKADLKGGYP-----FGGTDTDTKANEKDKEKEHTADDSLYECNICLDTAKDAVVSMCGHLFCWP 147
            ..::|..||.     :||.             |:..:.....|::..:|.||.          .|
Yeast   249 IASNLARGYSLPQSVYGGI-------------EYVQNAVAIGCDVTKETVKDN----------GP 290

  Fly   148 CLHQWLLTRPNRKL----CPVCKAAVDKDKVIPLYGRNSTHQEDPRNKVP 193
            ..|.:.:..|..|:    |.....||.|..|           :...||:|
Yeast   291 INHVYAIEIPLEKMLSDECFTASDAVHKKPV-----------KSSLNKIP 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32581	NP_001096988.2	RING	124..169	CDD:238093	9/48 (19%)
THI21	NP_015065.1	ThiD	22..298	CDD:223428	40/201 (20%)
THI21	NP_015065.1	TenA	331..551	CDD:223889
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1016
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950