DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32581 and rnf185

DIOPT Version :9

Sequence 1:	NP_001096988.2	Gene:	CG32581 / 318098	FlyBaseID:	FBgn0052581	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	XP_031753424.1	Gene:	rnf185 / 448093	XenbaseID:	XB-GENE-998723	Length:	189	Species:	Xenopus tropicalis

Alignment Length:	180	Identity:	103/180 - (57%)
Similarity:	125/180 - (69%)	Gaps:	12/180 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 GGTDTDTKANEKDKEKEHTADDSLYECNICLDTAKDAVVSMCGHLFCWPCLHQWLLTRPNRKLCP 163
            ||....|..       |.::.||.:|||||||||||||:|:||||||||||||||.|||||::||
Frog    18 GGASGSTNG-------EASSQDSTFECNICLDTAKDAVISLCGHLFCWPCLHQWLETRPNRQVCP 75

  Fly   164 VCKAAVDKDKVIPLYGRNSTHQEDPRNKVPPRPAGQRTEPDPVPGFPGFGFGD-GFHMSFGIGAF 227
            ||||.:.::||||||||.||.|||||.|.||||.|||.||:. .||.|||||| ||.||||||||
Frog    76 VCKAGISREKVIPLYGRGSTGQEDPREKTPPRPQGQRPEPEN-RGFQGFGFGDGGFQMSFGIGAF 139

  Fly   228 PFGFITSRLNFFEPRPPADI--RRLHEDEPWALSKLFWHFVVFVIYGLLV 275
            |||...:..|..:.|||..:  ...:.||.: ||:||....:.:::.||:
Frog   140 PFGIFATAFNINDGRPPPAVPGTPQYVDEQF-LSRLFLFVALVIMFWLLI 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32581	NP_001096988.2	RING	124..169	CDD:238093	39/44 (89%)
rnf185	XP_031753424.1	RING-HC_RNF185	36..78	CDD:319658	36/41 (88%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	134	1.000	Domainoid score	I4978
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	214	1.000	Inparanoid score	I3531
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1510545at2759
OrthoFinder	1	1.000	-	-		FOG0000717
OrthoInspector	1	1.000	-	-		otm49469
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X682
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060