Protein Alignment Muc14A and VIT

DIOPT Version :9

• Sequence 1: NP_727928.3
• Gene: Muc14A / 318097
• FlyBaseID: FBgn0052580
• Length: 16223
• Species: Drosophila melanogaster
• Sequence 2: NP_444506.2
• Gene: VIT / 5212
• HGNCID: 12697
• Length: 693
• Species: Homo sapiens
• Alignment Length: 615
• Identity: 112/615 - (18%)
• Similarity: 204/615 - (33%)
• Gaps: 152/615 - (24%)

  Fly 15482 QTLTFSKLSPTQIITEKSTSNNLSVHSNIDNSTISTQPYFDTDTTKYSTSVGVLSEESSK----- 15541
            |:|:..:...:.|:.|......::..|.:..|:              |.|....:.|::|
Human   122 QSLSLPRWRESFIVLESKPKKGVTYPSALTYSS--------------SKSPAAQAGETTKAYQRP 172

  Fly 15542 ----LTKQNITEEITTNILSLPSNIATSTTLTQPHSDTDKTEAIQNQTTAGHTTQDSSVIGLLSK 15602
                .|.|.:|   ...:|::...:||.|||.:|......|.:|....:.||.:|:..:
Human   173 PIPGTTAQPVT---LMQLLAVTVAVATPTTLPRPSPSAASTTSIPRPQSVGHRSQEMDL------ 228

  Fly 15603 EPTQTLTFSKLSPTQIITEKSTTNNLSVHSNI---DNSTISTQPYFDTDTTKYSTSVGVLS--EE 15662
              ..|.|::           |:.|.......|   |.|..:.|.....|     .|:|.:.  :.
Human   229 --WSTATYT-----------SSQNRPRADPGIQRQDPSGAAFQKPVGAD-----VSLGEMDSWKP 275

  Fly 15663 SSKLTKQNIT--EEITTNILSLPSNIATSTTLTQPHSDTDKTETIQNQTTAGHTTQDSSVIGLLS 15725
            .|.|..:.:.  ||::|..|.       ..:|..|:...|.:..|...|:.|  .:...:...|.
Human   276 GSVLLDEGLVPKEELSTQSLE-------PVSLGDPNCKIDLSFLIDGSTSIG--KRRFRIQKQLL 331

  Fly 15726 KEPTQTLTFSKLSPTQIITEKSTSNNLSVHSNIDNSTISTQPYFDTDTTKYSTSVGV--LSEASS 15788
            .:..|.|......|...:.:  ..:|.:.|.|:...|.|..  ..|...|.:...|:  :..|.|
Human   332 ADVAQALDIGPAGPLMGVVQ--YGDNPATHFNLKTHTNSRD--LKTAIEKITQRGGLSNVGRAIS 392

  Fly 15789 KLTKQNITEKSTTNILSLPSNIATSTTLTQPHFYTDKTETTGNQTSTEHTSKYSTTVEFLSKEQT 15853
            .:|| |...|:..|....| |:........|   |||.|...........:.:..|:|..::.:.
Human   393 FVTK-NFFSKANGNRSGAP-NVVVVMVDGWP---TDKVEEASRLARESGINIFFITIEGAAENEK 452

  Fly 15854 SII--PTFSK-----------------------LEP-------TEHISNNKKFTSNGTTEYVISQ 15886
            ..:  |.|:.                       |:|       |:.::.:|...::....:||..
Human   453 QYVVEPNFANKAVCRTNGFYSLHVQSWFGLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDG 517

  Fly 15887 SNN-KTYSDSQLISTTENLILTASSQPTDVNVWKEIDKRLDDLQNKYTIRDNNSLDNSEFKEKFS 15950
            |:: .|.:...::....|  ||...:.:|.      |.|:..:|  ||..........::..|..
Human   518 SSSVGTGNFRTVLQFVTN--LTKEFEISDT------DTRIGAVQ--YTYEQRLEFGFDKYSSKPD 572

  Fly 15951 QINSSIHLNQLPGNIRASLYANFTI-----------------------YDKIRI-----ELEAII 15987
            .:|:...:....|........||.:                       ||.:||     .|:.:|
Human   573 ILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKPNKRKLMILITDGRSYDDVRIPAMAAHLKGVI 637

  Fly 15988 LFKLN---QILENLKATKSTPACIDHYKYI 16014
            .:.:.   ...|.|:...:.|| .||..::
Human   638 TYAIGVAWAAQEELEVIATHPA-RDHSFFV 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Muc14A	NP_727928.3	PRK14949	<11377..11776	CDD:237863
		PRK08581	11922..>12215	CDD:236304
		PRK14949	<13679..14114	CDD:237863
		PRK14949	<14663..15055	CDD:237863
VIT	NP_444506.2	LCCL	44..133	CDD:281766	2/10 (20%)
		vWFA	308..471	CDD:294047	34/173 (20%)
		vWA_collagen	509..669	CDD:238749	30/169 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900