DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Muc14A and CG13252

DIOPT Version :9

Sequence 1:	NP_727928.3	Gene:	Muc14A / 318097	FlyBaseID:	FBgn0052580	Length:	16223	Species:	Drosophila melanogaster
Sequence 2:	NP_649248.3	Gene:	CG13252 / 40289	FlyBaseID:	FBgn0037016	Length:	384	Species:	Drosophila melanogaster

Alignment Length:	397	Identity:	81/397 - (20%)
Similarity:	137/397 - (34%)	Gaps:	146/397 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   909 STSRSNQPLPTKLHSVK------------DNAPHSL-------TNANPESLTSKDLTTKGNGVTD 954
            :|:...:|||....|||            .:..|:|       :|| .|...:.::.:..:||:.
  Fly    26 ATTLDQEPLPDLCQSVKCPPDAEMQCPADSSIRHNLLAVDLIKSNA-VELPNASEMASAADGVSY 89

  Fly   955 NKITTLSKLSSDNVCECTCLLEQGNDSCTC------NCMTDTNSIDESILTASQIVSSEDLQYSS 1013
            |:    ..:|.::..:| ||    |..|.|      :|.:|.   ||.::....:
  Fly    90 NR----GLISDEDYVQC-CL----NRKCVCKTCYIPDCPSDA---DEDVVVVELV---------- 132

  Fly  1014 NPPSYKSTQENTNTKGKNKNLSTLLQISSTGPYQIYQSEIGNQSQYVPPSSTLFSDITKISNTDK 1078
                    .||..|.|:           ..|.|:. |:|         |:.|:..|      ||.
  Fly   133 --------PENNQTPGE-----------CCGTYEC-QAE---------PNCTVVRD------TDF 162

  Fly  1079 D-----------------HPTLDEE-ENISKSPLHLSTTSSSLPKIQITGVSHLPFLSTISNIKF 1125
            .                 |.|.||. |.:.:|              :|:|:.:....:...|.|
  Fly   163 HWLKQCRRCKCESGLKICHKTCDERAEGVCQS--------------KISGMFYKDGENWTENCK- 212

  Fly  1126 EQSSFHGCDCTCQLEIGKDSCICE-CNLKESTSEGLKSVTASSLYIYLPQSSTTAHSLLTDLSAE 1189
                      ||:.|.|:..|... |......||....:..:...:..|:.:...|....|.|.|
  Fly   213 ----------TCECEKGEPKCTMSFCGNLNCPSEQQVMLKDTCCPVCWPKCAPMPHEKQDDGSYE 267

  Fly  1190 NQTNQEETSELSESLP-----QLTTEESSSFQESSAEENQMTEVPWTLTTSLSQSSSKTKNIFSS 1249
            :..::.||.| .:|||     .|||::|:             |:..|.||:.|..::.|..:..:
  Fly   268 DYVDESETPE-EDSLPPLLPDPLTTQQSA-------------ELVATSTTTSSNGTTSTTVVPLA 318

  Fly  1250 LSVNEDN 1256
            .:||.:|
  Fly   319 ATVNCNN 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Muc14A	NP_727928.3	PRK14949	<11377..11776	CDD:237863
		PRK08581	11922..>12215	CDD:236304
		PRK14949	<13679..14114	CDD:237863
		PRK14949	<14663..15055	CDD:237863
CG13252	NP_649248.3	VWC	197..249	CDD:302663	11/62 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900