Protein Alignment Muc14A and clec-223

DIOPT Version :9

• Sequence 1: NP_727928.3
• Gene: Muc14A / 318097
• FlyBaseID: FBgn0052580
• Length: 16223
• Species: Drosophila melanogaster
• Sequence 2: NP_505863.2
• Gene: clec-223 / 179561
• WormBaseID: WBGene00007282
• Length: 1034
• Species: Caenorhabditis elegans
• Alignment Length: 1125
• Identity: 263/1125 - (23%)
• Similarity: 413/1125 - (36%)
• Gaps: 290/1125 - (25%)

  Fly 14715 AEDQTNQEETSELSKSLPQLTTAESISFQESSAEQNQMTEEPWTLSTSLPQTSSKTNITFSSQSV 14779
            ||..|:....|..::|....:|:......||:|..:..||.|.|.||:.|.||::|..|   :|.
 Worm    91 AEKSTSTTTVSPTTESTAAPSTSTETPTTESTAAPSTSTETPTTESTAAPSTSTETPTT---EST 152

  Fly 14780 YEDKTSLEDTRTLSISQSITMTNSPLTDLSAEDQTNQEETSELSKSLPQLTTEESISFQESSAEQ 14844
            ....||.|...|.|.:...|.|.:|.|:.:|...|:.|..:..|.:.|..:||...:  ||:|..
 Worm   153 AAPSTSTETPTTESTAAPSTSTETPTTESTAAPSTSTETPTTESTAAPSTSTETPTT--ESTAAP 215

  Fly 14845 NQMTEEPWTLSTSLPQTSSKTNITFSSQSVNEDKTSLEDTRTLSISQSITMTNSLLTDLSAEDQT 14909
            :..||.|.|.||:.|.||::|..|   :|.....||.|...|.|.:...|.|.:..|:.:|...|
 Worm   216 STSTETPTTESTAAPSTSTETPTT---ESTAAPSTSTETPTTESTAAPSTSTETPTTESTAAPST 277

  Fly 14910 NQEETSELSKSLPQLTTEESISFQESSAEQNQMTEEPWTLSTSLPQSSSKTNNIFSSQSVNEDKT 14974
            :.|..:..|.:.|..:||...:  ||:|..:..||.|.|.||:.|.:|::|.   :::|.....|
 Worm   278 STETPTTESTAAPSTSTETPTT--ESTAAPSTSTETPTTESTAAPSTSTETP---TTESTAAPST 337

  Fly 14975 SLEDTRTLSTSQPITITNSPLTDLSAEDQTNQEETSVLSKSLPQLTTEESISFQESSAEQNQMTE 15039
            |.|...|.||:.|.|.|.:|.|      :|....||.:|:|.  :.||               .:
 Worm   338 STETPTTESTAAPSTSTETPTT------KTTIGSTSTISQSC--IETE---------------CD 379

  Fly 15040 EPW--TLSTSPPQSSSKTKNIFSSQSVNEEKTSLEDTRTLSISQSRAITNSLLTDLSAEDQTNK- 15101
            :.|  ||..:.||.:...| :||     .:.:|.:|.........:|    .||...:.|:.:|
 Worm   380 DGWIKTLRGNNPQKTLCMK-LFS-----HDTSSYDDASMYCYDSHQA----FLTGPDSNDEYDKI 434

  Fly 15102 --------EEISELSKSLPQLTTEESISFQESSAE--QNQMTEEP----WTLSTSPPQSSSNTI- 15151
                    :::|: |:|:..:..:.:......|.|  ||.:...|    |.....   .:|||:
 Worm   435 MEQALNISDQVSD-SQSMILIGLKRTTECTTDSGEQDQNSICRRPKGFIWQDGLG---ETSNTLI 495

  Fly 15152 -------KTTETSEEPLCLCTCVIDPDEDICSCNCKITKSIPTGRTTSKHSQWDGSSTKALGLDG 15209
                   ...|||.:.:..||.:|                |..|.|.:|:         ...||.
 Worm   496 NQHFNDDPGVETSPDHVRACTGII----------------IVKGATNNKN---------VYSLDC 535

  Fly 15210 TEDQKTFDATQNSMTIGLLSKEPTQTLTFSKLSTTQIITEKSTSNNLSVHSNIDKSTISTQPYFD 15274
            :..:|:.......:..|.|.|.|..|.  |.:||    |..::|:..||.|.|..||.:|.
 Worm   536 SNGEKSSGEKSKMVVCGKLGKCPATTP--STIST----TSGASSSTASVSSTILSSTATTM---- 590

  Fly 15275 TDTTKYSTSVGVLSEESSKLTKQNITEEITTNILSLPSNIATSTTLTQPHSDTDKTEAIQNQTTA 15339
                               :|....||:.:|...|.|::.|||||          |..|   ||.
 Worm   591 -------------------VTSTPTTEKSSTTTTSTPTSEATSTT----------TAMI---TTT 623

  Fly 15340 GHTTQDSSVVGLLSKEPTQTLTFSKLSPTQIITEKSTTNNLSVHSNIDKSTISTQPYFDTDTTKY 15404
            ..||::          ||.|     ..||::.       ....|..|....:.....|......|
 Worm   624 SGTTEN----------PTTT-----DCPTKVC-------RYGFHPTIRNGKVWCIRVFFHFVLNY 666

  Fly 15405 STSVGVLSEESSKLTKQNITEEITTNILSLPSNIATSTTLTQPHSDTDKTEAIQNQTTAGHTTQD 15469
            ...                 .:...|..        .:||:.| :|.::...:.:||..     |
 Worm   667 QDG-----------------SDYCWNYF--------HSTLSGP-ADENEYNVLLDQTKT-----D 700

  Fly 15470 SSVIGLLSKEPTQTLTFSKLSPTQIITEKSTS--NNLSVHSNIDNSTIST---------QPYFDT 15523
            .|::..|:|.....:..........:.|.|::  ...|.:..:||.|.:|         ||  ||
 Worm   701 PSLVQSLTKYTKVFMVLGAQRTPACLYESSSAQCEKPSGYQWLDNVTDTTYAFTKFNEDQP--DT 763

  Fly 15524 DTTKYSTSVGVLSEESSKLTKQNITEEITTNILSLPSNIATSTTLTQPHSDTDKTEAIQNQTTAG 15588
            ...:....||||.....  ||::  :|:   :.||..|.|.|.     |      :.:......|
 Worm   764 SPEQPEGCVGVLVYTDP--TKRD--KEL---VWSLSCNDAQSA-----H------QVVLKLVVCG 810

  Fly 15589 H--TTQDSSVIGLLSKEPTQTLTFSKLSPTQIITEKSTTNNLSVHSNID--------NSTISTQP 15643
            |  ...:.|.|...|.:.|.|:.    |.|...|..|||..:...|::.        |.| ||.|
 Worm   811 HEGVCPEESTIPPPSTQSTTTMK----STTTATTSMSTTKKVCAKSDLKCANGWTSFNRT-STNP 870

  Fly 15644 YFDTDTTKYSTSVGVLSEESSKLTK---------QNITE-EITTNILSLPSNIATS------TTL 15692
            :.....:.|:.|.    |:|..|..         :|||| :....:.....:.:||      .|:
 Worm   871 FCFKVISSYNQSY----EQSEALCAASGGYLSGVENITEYQFAVELAKAAVDYSTSFNEKILVTI 931

  Fly 15693 TQPHS----DTDKTET---------IQNQTTAGHTTQDSSV----------------IGLLSKEP 15728
            .....    .||.||:         :.::|......|..|:                :|::..:.
 Worm   932 ALKRKVICLQTDSTESCITFKAYEFVDDKTKYVAILQHYSLWADNQPVIISDQPHGCVGIMVTQS 996

  Fly 15729 TQTLTFSKLSPTQIITEKST 15748
            |.|...|||..|:..|...|
 Worm   997 TSTSGDSKLFSTRCETGTQT 1016

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Muc14A	NP_727928.3	PRK14949	<11377..11776	CDD:237863
		PRK08581	11922..>12215	CDD:236304
		PRK14949	<13679..14114	CDD:237863
		PRK14949	<14663..15055	CDD:237863	103/341 (30%)
clec-223	NP_505863.2	CLECT	856..1012	CDD:214480	31/160 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000