Protein Alignment Muc14A and COCH

DIOPT Version :9

• Sequence 1: NP_727928.3
• Gene: Muc14A / 318097
• FlyBaseID: FBgn0052580
• Length: 16223
• Species: Drosophila melanogaster
• Sequence 2: NP_001334649.1
• Gene: COCH / 1690
• HGNCID: 2180
• Length: 615
• Species: Homo sapiens
• Alignment Length: 623
• Identity: 120/623 - (19%)
• Similarity: 190/623 - (30%)
• Gaps: 223/623 - (35%)

  Fly 15136 PWTLSTSPPQSSSNTIKTTE-----TSEEPLCLCTCV-------------IDPDED----ICSCN 15178
            ||. |..||:.....::...     |....|.|.||.             :|..::    :|...
Human    55 PWA-SALPPEEEGAKVEPPRGAPALTPAADLLLLTCFSHAPIAITCFTRGLDIRKEKADVLCPGG 118

  Fly 15179 CKITKSIPTG----------------RTTSKHSQWDGSSTKALGLDGTEDQKTFDATQNSMTIGL 15227
            |.:.:....|                |....:|   |...:...|.|.|:..:.||  |.:...:
Human   119 CPLEEFSVYGNIVYASVSSICGAAVHRGVISNS---GGPVRVYSLPGRENYSSVDA--NGIQSQM 178

  Fly 15228 LSK-EPTQTLTFSKLSTTQIITEKSTSNNLSVHSNIDKSTISTQPYFDTDTTKYSTSVGVLSEES 15291
            ||: ..:.|:|..| |:||..|.::.|   :.|....|....| |...|........:..|.:.|
Human   179 LSRWSASFTVTKGK-SSTQEATGQAVS---TAHPPTGKRLKKT-PEKKTGNKDCKADIAFLIDGS 238

  Fly 15292 SKLTKQ--NITEEITTNILSLPSNIATSTTLTQPH------SDTDKTE-AIQNQTTA-------- 15339
            ..:.::  |:.:.....: :|...|.|.    .||      |:..|.| .::|.|:|
Human   239 FNIGQRRFNLQKNFVGKV-ALMLGIGTE----GPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIK 298

  Fly 15340 ---------------GHTTQDSSVV--GLLSKEPTQTLTFSKLSPTQIITE-------------- 15373
                           .||.|....|  |:....|...:.|....|:..|.|
Human   299 EVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFI 363

  Fly 15374 ----KSTTNNLSVHSN---IDKSTISTQPYFD------TDTTKY--------------------- 15404
                |.....|.:..:   :||:......:|.      ..||||
Human   364 VSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCY 428

  Fly 15405 -STSVGVLSEESSKLTKQNITEEITTNILSLPSNIATSTTLTQPHSDTD-KTEAIQNQTTAGHTT 15467
             |.::..|.:.||.:...|.     ..:|...||||.:..:    ||.. |..|:|       .|
Human   429 NSVNIAFLIDGSSSVGDSNF-----RLMLEFVSNIAKTFEI----SDIGAKIAAVQ-------FT 477

  Fly 15468 QDSSVIGLLSKEPTQTLTFSKLSPTQIITEKSTSNN-LSVHSNIDNSTISTQPYFDTDTTKYSTS 15531
            .|            |...||       .|:.||..| |:|..||                :| .|
Human   478 YD------------QRTEFS-------FTDYSTKENVLAVIRNI----------------RY-MS 506

  Fly 15532 VGVLSEESSKLTKQNITEEITTNILSLPSNIATSTTLTQPHSDTDKTEAIQNQTTAGHTTQDSSV 15596
            .|..:.::...|.:|:...|..   |...|.....|..|.:.|      :|....|.|   |:.:
Human   507 GGTATGDAISFTVRNVFGPIRE---SPNKNFLVIVTDGQSYDD------VQGPAAAAH---DAGI 559

  Fly 15597 ----IGL----------LSKEPTQ-----TLTFSKLSP 15615
                :|:          ::.:|.:     |..|:.|.|
Human   560 TIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEP 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Muc14A	NP_727928.3	PRK14949	<11377..11776	CDD:237863
		PRK08581	11922..>12215	CDD:236304
		PRK14949	<13679..14114	CDD:237863
		PRK14949	<14663..15055	CDD:237863
COCH	NP_001334649.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900