DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32579 and ADGB

DIOPT Version :9

Sequence 1:	NP_001259606.1	Gene:	CG32579 / 318096	FlyBaseID:	FBgn0052579	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_078970.3	Gene:	ADGB / 79747	HGNCID:	21212	Length:	1667	Species:	Homo sapiens

Alignment Length:	359	Identity:	63/359 - (17%)
Similarity:	128/359 - (35%)	Gaps:	104/359 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 PISKLSMLLTVVSILWRFVSICINWSLAYVYWME---------ESYGYCAWTIGSILVPMVVTSV 72
            |:.:..:|....|.:...:.||.  .:::|...|         ||   |.:|..|:|:...:.:|
Human   744 PVGRHMLLFNAYSPVGHSIHICS--MVSFVIGDEHVVLPNFEPES---CRFTEQSLLIMKAIGNV 803

  Fly    73 IYIHTLKSAHAGEKRILERGVYSNAVISYLFRDVYVLNYAFKYSLAKERDDKQAEIEYYQKLMTE 137
            |            ....::|..|.|:     :|:...:|...:      .||:...::::..
Human   804 I------------ANFKDKGKLSAAL-----KDLQTAHYPVPF------HDKELTAQHFRVF--- 842

  Fly   138 ECNVSFVRLFDSFLESAPQKILQLAI--------LLQSTLEFTYYRHIALIVYFGNIAWCI---- 190
              ::|..||......:.|....:.|.        ||.|:||     .::|:.:. ::.:|:
Human   843 --HLSLWRLMKKVQITKPPPNFKFAFRAMVLDLELLNSSLE-----EVSLVEWL-DVKYCMPTSD 899

  Fly   191 QAYNHSNRLAQLDKHDIAAKGRFLQFLFLLCL-----------TVIRFYFVVSRTLCIAYVASIF 244
            :.|: :..:|...|.....:|.:::.|....:           |:.:.:.|:...| ..|..|:.
Human   900 KEYS-AEEVAAAIKIQAMWRGTYVRLLMKARIPDTKENISVADTLQKVWAVLEMNL-EQYAVSLL 962

  Fly   245 PIETLIICATL---ACFYG--TIVFFVDSPMIAKSRPMNYSYCLCFGVVYLFIFTPVKDAPTKYK 304
            .:.....|.:|   .|:..  |.:.|.|..:..:.:|                       |..:.
Human   963 RLMFKSKCKSLESYPCYQDEETKIAFADYTVTYQEQP-----------------------PNSWF 1004

  Fly   305 YAFYLTFCLLQNIIACALYIPLYLATAIIALYIV 338
            ..|..||.:.|::|   |...:|....|..|:||
Human  1005 IVFRETFLVHQDMI---LVPKVYTTLPICILHIV 1035

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32579	NP_001259606.1	XK-related	25..353	CDD:286853	61/351 (17%)
ADGB	NP_078970.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..45
		CysPc	<192..>299	CDD:294044
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	347..387
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	540..566
		Mb_like	<780..853	CDD:271266	18/103 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1297..1355
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1420..1522
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1646..1667
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900