DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32579 and Capn11

DIOPT Version :9

Sequence 1:	NP_001259606.1	Gene:	CG32579 / 318096	FlyBaseID:	FBgn0052579	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_001002806.2	Gene:	Capn11 / 408218	RGDID:	1302946	Length:	715	Species:	Rattus norvegicus

Alignment Length:	167	Identity:	30/167 - (17%)
Similarity:	63/167 - (37%)	Gaps:	36/167 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 WMEESYGYCAWTIGSIL--VPMVVTSVIYIHTLKSAHAGEKRILERGVYSNAVISYLFRDVYVLN 110
            |.....|....|||.::  ||....::..||..|....         .|.:...|.:|.:...:|
  Rat   430 WRHAREGPQLLTIGFVVFSVPKEFQNLQDIHLKKDFFM---------KYRDHGFSEIFTNTREVN 485

  Fly   111 YAFK-----YSLAKERDDKQAEIEYYQKLMTEECNVSFVRLFDSFLESAPQKILQLAILLQSTLE 170
            ...:     |.:.....:...:.::..::.||:.:.:::....:.||...::.:..|.|.|:::|
  Rat   486 SHLRLPPGEYVIIPSTFEPHKDADFLLRVFTEKHSETWLLDEVNMLEQLQEETITDADLDQNSVE 550

  Fly   171 FTYYRHIALIVYFGNIAWCIQAYNHSNRLAQLDKHDI 207
            .           |..:|         ||.:|:|.:|:
  Rat   551 L-----------FETLA---------NRDSQVDMYDL 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32579	NP_001259606.1	XK-related	25..353	CDD:286853	30/167 (18%)
Capn11	NP_001002806.2	Peptidase_C2	56..352	CDD:279042
		Calpain_III	367..520	CDD:279416	17/98 (17%)
		Linker. /evidence=ECO:0000250\|UniProtKB:Q9UMQ6	528..543		2/14 (14%)
		Domain IV. /evidence=ECO:0000250\|UniProtKB:Q9UMQ6	544..714		10/44 (23%)
		EFh	591..641	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900