DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32579 and XKR7

DIOPT Version :9

Sequence 1:	NP_001259606.1	Gene:	CG32579 / 318096	FlyBaseID:	FBgn0052579	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_001011718.1	Gene:	XKR7 / 343702	HGNCID:	23062	Length:	579	Species:	Homo sapiens

Alignment Length:	378	Identity:	75/378 - (19%)
Similarity:	144/378 - (38%)	Gaps:	76/378 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 WSLAYVYWMEESYGYCAWTIGSILVPMVVTSV------IYIHTLKSAHAGEKRILERGVYSNAVI 99
            | ||..|:::..:.|.:.|:..:|:|.:|..:      :|.::..:...|.....:..|...|.|
Human    76 W-LAASYYLQNQHTYFSLTLLFVLLPSLVVQLLSFRWFVYDYSEPAGSPGPAVSTKDSVAGGAAI 139

  Fly   100 S---------------------------------------------YLFRDVYVLNY--AFKYSL 117
            |                                             :|.:...|..|  |....|
Human   140 STKDSAGAFRTKEGSPEPGPQPAPSSASAYRRRCCRLCIWLLQTLVHLLQLGQVWRYLRALYLGL 204

  Fly   118 AKERDDKQAEIEYYQKLMTEECNVSFVRLFDSFLESAPQKILQLAILLQSTLEFTYYRHIALIVY 182
            ......::....:|.:::.|..:||.:||.::||.||||.:|||::|:...........::....
Human   205 QSRWRGERLRRHFYWQMLFESADVSMLRLLETFLRSAPQLVLQLSLLVHRGGAPDLLPALSTSAS 269

  Fly   183 FGNIAWCIQAYNHSNRLAQLDKHDIAAKGRFLQFLFLLCLTVIRFYFVVSRTLCIAYVASIFPIE 247
            ..::||.:.:|....|.::.||..::.||...|.|:.|       :.:.:|.|..|..||::.:.
Human   270 LVSLAWTLASYQKVLRDSRDDKRPLSYKGAVAQVLWHL-------FSIAARGLAFALFASVYKLY 327

  Fly   248 TLIICATLACFYGTIVFFV--DSPMIAKSRPMNYSYCLCFGVVYLFIFTPVKDAPTKYKYAFYLT 310
            ..|......|   .:.|:|  .......|:.....|.:..|::|:|.:..||:..::.:...|..
Human   328 FGIFIVAHWC---VMTFWVIQGETDFCMSKWEEIIYNMVVGIIYIFCWFNVKEGRSRRRMTLYHC 389

  Fly   311 FCLLQNIIACAL----------YIPLYLATAIIALYIVGIVLLIIYYTYCHPN 353
            ..||:|......          :..|.:...:.:.:.:||..:.:||...|||
Human   390 IVLLENAALTGFWYSSRNFSTDFYSLIMVCVVASSFALGIFFMCVYYCLLHPN 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32579	NP_001259606.1	XK-related	25..353	CDD:286853	73/376 (19%)
XKR7	NP_001011718.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..40
		XK-related	59..442	CDD:286853	73/376 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	146..166		0/19 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	466..510
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	84	1.000	Domainoid score	I8229
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1230316at2759
OrthoFinder	1	1.000	-	-		FOG0001048
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16024
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5206
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	7.050