DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32579 and Capn2

DIOPT Version :9

Sequence 1:	NP_001259606.1	Gene:	CG32579 / 318096	FlyBaseID:	FBgn0052579	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_058812.1	Gene:	Capn2 / 29154	RGDID:	2268	Length:	700	Species:	Rattus norvegicus

Alignment Length:	214	Identity:	43/214 - (20%)
Similarity:	63/214 - (29%)	Gaps:	84/214 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 WRFVSICINW----------SLAYVYWMEESY----------------GYCAWTIGSIL------ 64
            |:...:..||          :....:||...|                | |.:.:|.|.
  Rat   356 WKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDDEDGERG-CTFLVGLIQKHRRRQ 419

  Fly    65 ----------------VPMVVTSVIYIHTLKSAHAGEKRILERGVYSNAVISYLFRDV------- 106
                            ||..:|....||..|:... ..|..||   |:..|:  .|:|
  Rat   420 RKMGEDMHTIGFGIYEVPEELTGQTNIHLSKNFFL-TTRARER---SDTFIN--LREVLNRFKLP 478

  Fly   107 ---YVL---------NYAFKYSLAKER--------DDKQAEIEYYQKLMTEECNVSFVRLFDSFL 151
               |||         |..|...:..|:        |:.:|.||..: ...|:....|.|||....
  Rat   479 PGEYVLVPSTFEPHKNGDFCIRVFSEKKADYQTVDDEIEANIEEIE-ANEEDIGDGFRRLFAQLA 542

  Fly   152 -ESAPQKILQLAILLQSTL 169
             |.|.....:|..:|:..|
  Rat   543 GEDAEISAFELQTILRRVL 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32579	NP_001259606.1	XK-related	25..353	CDD:286853	43/214 (20%)
Capn2	NP_058812.1	Peptidase_C2	46..342	CDD:279042
		Domain III	345..514		29/164 (18%)
		Calpain_III	356..507	CDD:279416	29/157 (18%)
		Linker	515..529		3/14 (21%)
		Domain IV	530..700		9/32 (28%)
		EFh	577..631	CDD:238008
		FRQ1	604..>696	CDD:227455
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900