DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32579 and clp-3

DIOPT Version :9

Sequence 1:	NP_001259606.1	Gene:	CG32579 / 318096	FlyBaseID:	FBgn0052579	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_493052.3	Gene:	clp-3 / 173089	WormBaseID:	WBGene00000544	Length:	752	Species:	Caenorhabditis elegans

Alignment Length:	233	Identity:	39/233 - (16%)
Similarity:	73/233 - (31%)	Gaps:	68/233 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DALMMGPISKLSMLLTVVSILWRFVSICIN-----WSLAYVYWMEESYGYCAWTIGSILVPMVVT 70
            |..|...::.|:|::..|.:  ..:.:|:|     ..:.....:.:.||||...:..:.......
Worm   435 DIFMADEMAVLAMIMRGVQM--GSLIVCLNIDVNEKGVRQKNGLIKGYGYCITGVNLMETEWEKA 497

  Fly    71 SVIYIHT--------------------LKSAHAGEKRILERGVYSNAVISYL--FRDVYVLNYAF 113
            .:|.|.:                    |........||.|.|.:..::..::  |.|||..|.:
Worm   498 PLIRIRSPWGKVKWKGDFCYRSHRWFGLDKEKRESFRIKEDGEFWMSLKDFMVEFTDVYCCNLS- 561

  Fly   114 KYSLAKERDDKQAEIEYYQKLMTEECNVSF-----------------------------VRLFDS 149
              :......:|..|::..:....:....||                             .|..||
Worm   562 --ADTMHEVEKMTEVKVMEHQSQQWIQASFEGEWSSRIGTAGGCDDHDTFCTNLQYEIHFRATDS 624

  Fly   150 FLESAPQKILQLAILLQSTLEFTYYRH-----IALIVY 182
            :  .:..|...:|.|.|...:...|:.     |.|:||
Worm   625 Y--DSNHKCTIIAALFQKNRDHCVYKGLELFLIGLLVY 660

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32579	NP_001259606.1	XK-related	25..353	CDD:286853	35/219 (16%)
clp-3	NP_493052.3	MDN1	<5..136	CDD:227596
		CysPc	254..559	CDD:238004	22/125 (18%)
		Calpain_III	582..732	CDD:238132	14/81 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900