DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32579 and Capn1

DIOPT Version :9

Sequence 1:	NP_001259606.1	Gene:	CG32579 / 318096	FlyBaseID:	FBgn0052579	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_001103974.1	Gene:	Capn1 / 12333	MGIID:	88263	Length:	713	Species:	Mus musculus

Alignment Length:	178	Identity:	36/178 - (20%)
Similarity:	62/178 - (34%)	Gaps:	62/178 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RTEV------DALMMGPISKLSMLLTVVSILWRFVSICINWSLAYVYWMEESYG----YCAWTIG 61
            ||::      |..::..|:.|::..|   ||.|.|        .|....::.|.    :..|..|
Mouse   104 RTDICQGALGDCWLLAAIASLTLNET---ILHRVV--------PYGQSFQDGYAGIFHFQLWQFG 157

  Fly    62 -------SILVPMVVTSVIYIHT----------LKSAHA---GEKRILERGVYSNAVISYLFRDV 106
                   ..|:|.....::::|:          |:.|:|   |....|..|..|.|     |.|
Mouse   158 EWVDVVIDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEA-----FED- 216

  Fly   107 YVLNYAFKYSLAKERDDKQAEIEYYQ---------KLMTEECNVSFVR 145
                  |...:.:..|.::|..:.||         .|:....|:|.:|
Mouse   217 ------FTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIR 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32579	NP_001259606.1	XK-related	25..353	CDD:286853	31/154 (20%)
Capn1	NP_001103974.1	Peptidase_C2	56..352	CDD:279042	36/178 (20%)
		Domain III	355..525
		Calpain_III	366..518	CDD:279416
		Linker	526..541
		PTZ00184	537..680	CDD:185504
		Domain IV	542..712
		EF-hand_8	556..609	CDD:290545
		EFh	589..643	CDD:238008
		EFh	622..704	CDD:298682
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0045
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900