DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2004 and CG10559

DIOPT Version :9

Sequence 1:	NP_001259353.1	Gene:	CG2004 / 31809	FlyBaseID:	FBgn0030060	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_651382.2	Gene:	CG10559 / 43063	FlyBaseID:	FBgn0039323	Length:	415	Species:	Drosophila melanogaster

Alignment Length:	391	Identity:	88/391 - (22%)
Similarity:	163/391 - (41%)	Gaps:	45/391 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 DEIIRNAGGTRHTSYK-FGPSG--KKGDAYLSRVFRITIYGVKEAEEGQDEKQLEISVIVKAMPD 81
            :|::....|..:...| |.|..  |.|:.|.:.:.|:     |...|.||.....:|.::|...|
  Fly    20 EELLSKRYGGNYAGIKSFKPEAGLKPGENYSTIMLRL-----KLEVELQDHTIENVSYMLKTPYD 79

  Fly    82 NLHRRRLFRSVIFFRNEINFYTKVLPAIEAFQKSRQPAPKKPFVEYPRCLASLCDGVNDFIALED 146
            ....|.:.|....|..|.:.:.:|:|.:|...|......|.....|.      .|..:|::.|:|
  Fly    80 FEMYREILRKNNMFAVERDVFIQVIPELEQMYKDVGVEVKFGAKAYE------IDAPDDYVLLQD 138

  Fly   147 VGPRGYRAPVRQDYISLEDALLTMRTLGRFHGVALAFNALDSKNFEKAAGSLEETY----YGEHT 207
            :||.|:|...|.:.:.:......::.:.::|.|:.....|        .|...:.|    |.:..
  Fly   139 LGPLGFRNVDRLEGLDMVHTKCVLKKMAQWHAVSATRIHL--------KGPYPQNYLQPTYADTM 195

  Fly   208 REWYTGFLLLAENVATDAVK--QIYPNSKYETVATNFLQPPLFDDLINLVST--RSKLSVFGHGD 268
            :|   ....:||.:....:|  .:|...:..:.|.:.:||.:. ||:..::|  ....:...|||
  Fly   196 KE---SIEQVAETLGKYFLKCLPLYEGYEEYSAAVHKMQPKIV-DLMYAMNTPDPQDFNALNHGD 256

  Fly   269 CWTPNFLTKY-NERGQSEEIIIIDFQLARCSSLALDLSFFIYSCTSQELREQHYDELLRAYLESA 332
            |||.|.:.|| :|..:..|...:|.||.:.:|:|.||.:|:...|..|::...:|..::.|.:..
  Fly   257 CWTSNIMFKYEDESPEPIETYFVDLQLPKVTSVAYDLIYFLLGSTKFEIQLSQFDYFIKYYHDHL 321

  Fly   333 QDLIQDLGGNAESIISWESLQEELKNFGRFGCGMGIESLPMTMMEDDEVADL----------DGI 387
            .:.::.|........:...|..:|..:||.|..:.....|..:::..|.|:|          ||:
  Fly   322 VEHLRMLNYPEAKTPTLGFLHTQLLKYGRVGYHIAFILCPPVLLDRTEDANLTDFVTETDNGDGL 386

  Fly   388 K 388
            |
  Fly   387 K 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2004	NP_001259353.1	EcKinase	42..340	CDD:281023	69/306 (23%)
CG10559	NP_651382.2	EcKinase	45..330	CDD:281023	70/307 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	3	3.010