DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2004 and CG6830

DIOPT Version :9

Sequence 1:	NP_001259353.1	Gene:	CG2004 / 31809	FlyBaseID:	FBgn0030060	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster

Alignment Length:	362	Identity:	88/362 - (24%)
Similarity:	162/362 - (44%)	Gaps:	37/362 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 KKGDAYLSRVFRITIYGVKEAEEGQDEKQLEISVIVKAMPDN--LHRRRLFRSVIFFRNEINFYT 103
            |.||.:.|::.::.|    ||:. :|......|.|:|...||  ::    |.....|..||..|:
  Fly   515 KPGDNFASKLLKVEI----EAQL-KDNSVKTFSYILKVHSDNDAIN----FSDFNLFPKEIEVYS 570

  Fly   104 KVLPAIEAFQKSRQPAPKKPFVEYPRCLASLCDGVNDFIALEDVGPRGYRAPVRQDYISLEDALL 168
            ..:||.|.|.|.    ...|....|:......|...:::.||::.|.|::...|...:.||.:..
  Fly   571 TYVPAFERFYKD----VGLPVTFSPKSFRLSKDVSKEYLLLENLQPSGFKMVDRMIGMDLEHSKC 631

  Fly   169 TMRTLGRFHGVALAFNALDSKNFEKAAGSLEETYYGEHTREWYTGFLLLAENVATDAVKQIYPNS 233
            |::.|.::|..:|.:..|:.....|....:    :.|.|...:.|..:   |.....::::   |
  Fly   632 TLKKLAQWHAASLKYKELNGPYSPKYNNGI----FTEQTAPIFKGMFV---NTKKSFIEEV---S 686

  Fly   234 KYETVATNFL--QPPLFDDLINLVSTRSKL-----SVFGHGDCWTPNFLTKYNERGQSEEIIIID 291
            |::.| ..:|  .|.:.|..::.:...:|:     :|..|||.|..|.:.:|...|:.:|.:::|
  Fly   687 KFDGV-DEYLHKMPEILDTYVDRILEDAKINEQAFNVLNHGDAWINNIMFQYESDGRVKETLLLD 750

  Fly   292 FQLARCSSLALDLSFFIYSCTSQELREQHYDELLRAYLESAQDLIQDLGGNAESIISWESLQEEL 356
            .|:.:..:.|.||.:||.|.|..:::...:|.|:|.|.::.::..:.|..|. .|.|.:.|...|
  Fly   751 HQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDYLIRWYHQNMKEHAKLLNYNG-FIPSLKELHAIL 814

  Fly   357 KNFGRFGCGMGIESLPMTMME--DDEVAD-LDGIKEN 390
            .....|..|..:.:|.|.:.:  ||...| ..|.:||
  Fly   815 IQHPIFAAGTVLTTLSMCLNKTTDDFTTDSFLGNEEN 851

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2004	NP_001259353.1	EcKinase	42..340	CDD:281023	71/306 (23%)
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	72/307 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010