DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2004 and CG5126

DIOPT Version :9

Sequence 1:	NP_001259353.1	Gene:	CG2004 / 31809	FlyBaseID:	FBgn0030060	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_608584.1	Gene:	CG5126 / 33306	FlyBaseID:	FBgn0031320	Length:	455	Species:	Drosophila melanogaster

Alignment Length:	461	Identity:	118/461 - (25%)
Similarity:	188/461 - (40%)	Gaps:	87/461 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RHTSY----KFGPSG---------KKG-DAYLSRVFRITIYGVKEAEEGQDEKQLEISVIVKAMP 80
            ||..|    .||||.         ..| |.::|.::.:|: .|..||    .|:.|: |:||.|.
  Fly    13 RHLVYDIFKNFGPSASLESHSVECSNGLDGFMSALYTVTL-DVVIAE----RKRTEV-VLVKFMK 71

  Fly    81 DNLHRRRLFRSVIFFRNEINFYTKVLPAIEAFQKSR--QPAPKKPFVEYPRC-------LASLCD 136
            .....|....|.|.|.|||..|.::|||.|...::.  :....|.:|  |.|       :..|.:
  Fly    72 GTEEFRESSNSYIQFSNEIFAYAEILPAYENVLRTSHLESEVVKNWV--PCCYFARFGHVEGLGN 134

  Fly   137 GVNDFIALEDVGPRGY----RAPVRQDYISLEDALLTMRTLGRFHGVALAFNALD-SKNFEKAAG 196
            |....:||:.:...||    |..:|:|.:   :|::.:  :|.||.:..|...|. :.:....||
  Fly   135 GRESVLALKHLKGDGYQLGPRLTLRRDQL---EAMVGL--VGPFHALGYATKILQPNVHARLRAG 194

  Fly   197 SLEETYYGEHTREWYTGFLLLAENVATDAVKQIYPNSKYETV---------------ATNFLQPP 246
            .::..:.....:    |...:...||.|...:.|...|.:.:               ...|.||.
  Fly   195 VVDMPFVSSSGK----GIFDVLYRVAFDRFYEFYDRQKEQLLQGADPGFGAAIERLREKYFKQPT 255

  Fly   247 LFDDLINLVS-----TRSKLSVFGHGDCWTPNFLTKYNERGQSEEIIIIDFQLARCSSLALDLSF 306
            |..:.|...|     ..|..:.|.|||....|.|..|....:.:.|..||||..|.|:.|:||||
  Fly   256 LLLERIRTSSFAEDQPDSHFATFLHGDYNRNNVLFHYGAEDKVDAIKAIDFQELRFSTTAIDLSF 320

  Fly   307 FIYSCTSQELREQHYDELLRAYLESAQDLIQ-DLGGNAESI-----------ISWESLQEELKNF 359
            |:|..|..|.|::.|.:|||.|..|..:::: .|..|...:           .|:|......|.:
  Fly   321 FMYMNTPSEGRKEIYADLLRKYHRSMIEMLELVLRRNRNELTDDRVDQLLQEYSFERFNAHFKRY 385

  Fly   360 GRFGCGMGIESLPMTMMEDDEVADLDGIKENAILTDIWNITPFKES---AKQQRLADIFK---HA 418
            ..:|..:.:..||..:..:.:.|:|..:.|    ||:......:.|   |..:...:|||   ||
  Fly   386 AFYGPMVCMHFLPWLLGTEKDCAELSRLFE----TDMHGPAFHQLSLDIAGDEANQEIFKTVRHA 446

  Fly   419 IDQGYI 424
            .:.||:
  Fly   447 YEHGYM 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2004	NP_001259353.1	EcKinase	42..340	CDD:281023	89/333 (27%)
CG5126	NP_608584.1	EcKinase	41..353	CDD:281023	88/328 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010