DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hexo2 and HEXO3

DIOPT Version :9

Sequence 1:	NP_525081.1	Gene:	Hexo2 / 31808	FlyBaseID:	FBgn0041629	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_176737.2	Gene:	HEXO3 / 842871	AraportID:	AT1G65590	Length:	535	Species:	Arabidopsis thaliana

Alignment Length:	599	Identity:	188/599 - (31%)
Similarity:	282/599 - (47%)	Gaps:	127/599 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 VAGLQYAPEIFESQRDCRLSCGKYGAIWPMPTGKECTISH--RRVRFDPWKVRFHVVAPGEA--- 126
            :||...|.|..|..|           |||:|    ..:||  ||:....   .|.:|..|..
plant    19 IAGTISAFEDIERLR-----------IWPLP----AQVSHGGRRMYLSG---DFKLVTEGSKYGD 65

  Fly   127 ATQFLRE-TNRLFVSNLLKECI---RNCTLETSKQIL--VRSTVANESLVLDWPTDESYALVVRT 185
            |:..|:| .:|:.....|...|   ||.:......:|  :...:::.:..|::..||||.|||.:
plant    66 ASGILKEGFDRMLGVVRLSHVISGDRNSSGTGGSALLQGLHVIISSSTDELEYGADESYKLVVPS 130

  Fly   186 TETATFVDIQATTVYGARHAFETLSNLVTGSLSNGL--LMVTTANITDRPAFSHRGVLLDTARNF 248
            .|..::..::|.:||||.|..:|.|.|...:|...:  :::|..||.|:|.||:||:|:||:|::
plant   131 PEKPSYAQLEAKSVYGALHGLQTFSQLCHFNLKKKVIEILMTPWNIIDQPRFSYRGLLIDTSRHY 195

  Fly   249 VPLKFIRSTLDAMAASKLNVLHWHVVDTHSFPLEITRVPEMQRYGAYSSSQTYSRQDALNLVKYA 313
            :||..|::.:|:|..:||||||||:|||.||||||...|::.. |||||||.|:.:||..:|.||
plant   196 LPLPVIKNVIDSMTYAKLNVLHWHIVDTQSFPLEIPSYPKLWN-GAYSSSQRYTFEDAAEIVNYA 259

  Fly   314 RLRGIRILIEIDGPSHAGNGWQWG---PAAGLGNMSVCLNQSPW-RRFCVQPPCGQLNPLNDHMY 374
            |.|||.:|.|||.|.||   ..||   ||.             | .:.|.:|    |:..:|..:
plant   260 RRRGIHVLAEIDVPGHA---LSWGKGYPAL-------------WPSKNCQEP----LDVSSDFTF 304

  Fly   375 AVLKEIFEDVAEVGAPEETLHMGGDEVFLPCWNNTDEIRDGMRARGYDLSEQSFLRLWSQFHQRN 439
            .|:..|..|.::: ...:.:|:|||||...||:.|..|..                 |.:.|:.:
plant   305 KVIDGILSDFSKI-FKFKFVHLGGDEVNTTCWSATPRIAQ-----------------WLKKHRMS 351

  Fly   440 LNAWDEINERMYPGIKEPKSVIIWSSHLTNPRYIETYLP-----KERFIIQTWVESQDALNRELL 499
                 |.....|..::..|..:.....:.|  :.||::.     ..:.::..|:.:  .|...:.
plant   352 -----EKEAYQYFVLRAQKIALSHGYEIIN--WEETFINFGSKLNRKTVVHNWLNT--GLVENVT 407

  Fly   500 QRGYRLIVSTKNAWYLDH------GFWGSTSYYNWRTVYSSGMPVGRSKDQ--VLGGEVCMWSEY 556
            ..|.|.|||.:..|||||      ||:.:..:.|          :...|.|  |||||||||.|:
plant   408 ASGLRCIVSNQEFWYLDHIDAPWQGFYANEPFQN----------ITDKKQQSLVLGGEVCMWGEH 462

  Fly   557 VDQNSLESRIWPRAGAAAERMWS-------NPKSSALLAQRRFYRYRERLLARGIHA------DA 608
            :|.:.:|..|||||.|||||:|:       ||.:    ...|...:|..|..||:.|      ..
plant   463 IDASDIEQTIWPRAAAAAERLWTPYAKLAKNPNN----VTTRLAHFRCLLNQRGVAAAPLVGGGR 523

  Fly   609 VIPHWCVLHEGQCL 622
            |:|    ...|.||
plant   524 VVP----FEPGSCL 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hexo2	NP_525081.1	Glycohydro_20b2	93..212	CDD:291511	37/129 (29%)
Hexo2	NP_525081.1	GH20_HexA_HexB-like	235..603	CDD:119332	130/391 (33%)
HEXO3	NP_176737.2	Glycohydro_20b2	34..157	CDD:373334	37/129 (29%)
HEXO3	NP_176737.2	GH20_HexA_HexB-like	182..512	CDD:119332	130/391 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54329
OrthoDB	1	1.010	-	-		D545162at2759
OrthoFinder	1	1.000	-	-		FOG0001678
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22600
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X846
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930