DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hexo2 and HEXO2

DIOPT Version :9

Sequence 1:	NP_525081.1	Gene:	Hexo2 / 31808	FlyBaseID:	FBgn0041629	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_001318927.1	Gene:	HEXO2 / 837064	AraportID:	AT1G05590	Length:	580	Species:	Arabidopsis thaliana

Alignment Length:	574	Identity:	183/574 - (31%)
Similarity:	275/574 - (47%)	Gaps:	81/574 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 IWPMPTGKECTISHRRVRFDPWKVRFHVVAP-----GEAATQF---LRETNRLFVSNLLKECIRN 149
            |||.|...... .|:.:...|   .|.::||     ..:.|::   :|..|   .|.|:...::.
plant    33 IWPKPRFLSWP-QHKAIALSP---NFTILAPEHQYLSASVTRYHNLIRSEN---YSPLISYPVKL 90

  Fly   150 CTLETSKQILVRSTVANESLVLDWPTDESYALVVRTTETATF-VDIQATTVYGARHAFETLSNLV 213
            ....|.:.::|  ||.:.||.|....||||.|.:   ...:| ..:.|.:.:||....||.|.::
plant    91 MKRYTLRNLVV--TVTDFSLPLHHGVDESYKLSI---PIGSFSAHLLAHSAWGAMRGLETFSQMI 150

  Fly   214 TGSLSNGLLMVTTANITDRPAFSHRGVLLDTARNFVPLKFIRSTLDAMAASKLNVLHWHVVDTHS 278
            .|: |..|.:.....|.|.|.|.||||||||:||:..:..|..|:.||:|:||||.|||:.|:.|
plant   151 WGT-SPDLCLPVGIYIQDSPLFGHRGVLLDTSRNYYGVDDIMRTIKAMSANKLNVFHWHITDSQS 214

  Fly   279 FPLEITRVPEMQRYGAYSSSQTYSRQDALNLVKYARLRGIRILIEIDGPSHAGNGWQWGPAAGLG 343
            |||.:...|.:...|:......|:.:|...:|:|....|:|:|.|||.|.|.|:   ||.|  ..
plant   215 FPLVLPSEPSLAAKGSLGPDMVYTPEDVSKIVQYGFEHGVRVLPEIDTPGHTGS---WGEA--YP 274

  Fly   344 NMSVCLNQSPW-------RRFCVQPPCGQLNPLNDHMYAVLKEIFEDVAEVGAPEETLHMGGDEV 401
            .:..|.|...|       .|...:|..||||||:...|.|:|.:.:|:.. ..||...|.|||||
plant   275 EIVTCANMFWWPAGKSWEERLASEPGTGQLNPLSPKTYEVVKNVIQDIVN-QFPESFFHGGGDEV 338

  Fly   402 FLPCWNNTDEIRDGMRARGYDLSEQSFLRLWSQFHQRNLNAWDEINERMYPGIKEPKSVIIWSSH 466
            ...|| .||...:...:.|..||:     |..::          ||..:...:.:.::|:.|...
plant   339 IPGCW-KTDPAINSFLSSGGTLSQ-----LLEKY----------INSTLPYIVSQNRTVVYWEDV 387

  Fly   467 LTNP--RYIETYLPKERFIIQTWVESQDALNRELLQRGYRLIVSTKNAWYLD--H-GFWGSTSYY 526
            |.:.  :...:.||||..|:|||....:...| ::..|||:|||:...:|||  | ||.|:.|.|
plant   388 LLDAQIKADPSVLPKEHTILQTWNNGPENTKR-IVAAGYRVIVSSSEFYYLDCGHGGFLGNDSIY 451

  Fly   527 N---------------WRTVYSSGMPVGRSKDQ----VLGGEVCMWSEYVDQNSLESRIWPRAGA 572
            :               |:::|:..:..|...::    ||||||.:|||..|...|:||:||||.|
plant   452 DQKESGGGSWCAPFKTWQSIYNYDIADGLLNEEERKLVLGGEVALWSEQADSTVLDSRLWPRASA 516

  Fly   573 AAERMWSNPKSSALL-----AQRRFYRYRERLLARGIHADAVIPHWCVLHEGQC 621
            .||.:||..:....:     |..|...:|.|::.|||.|:.:.|.||:.:.|.|
plant   517 LAESLWSGNRDERGVKRCGEAVDRLNLWRYRMVKRGIGAEPIQPLWCLKNPGMC 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hexo2	NP_525081.1	Glycohydro_20b2	93..212	CDD:291511	33/127 (26%)
Hexo2	NP_525081.1	GH20_HexA_HexB-like	235..603	CDD:119332	135/403 (33%)
HEXO2	NP_001318927.1	Glycohydro_20b2	33..149	CDD:373334	33/127 (26%)
HEXO2	NP_001318927.1	GH20_HexA_HexB-like	171..552	CDD:119332	135/403 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	232	1.000	Domainoid score	I643
eggNOG	1	0.900	-	-		E1_COG3525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	283	1.000	Inparanoid score	I864
OMA	1	1.010	-	-		QHG54329
OrthoDB	1	1.010	-	-		D545162at2759
OrthoFinder	1	1.000	-	-		FOG0001678
OrthoInspector	1	1.000	-	-		otm3150
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22600
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X846
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.980