DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hexo2 and HEXO1

DIOPT Version :9

Sequence 1:	NP_525081.1	Gene:	Hexo2 / 31808	FlyBaseID:	FBgn0041629	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_567017.2	Gene:	HEXO1 / 824692	AraportID:	AT3G55260	Length:	541	Species:	Arabidopsis thaliana

Alignment Length:	553	Identity:	168/553 - (30%)
Similarity:	262/553 - (47%)	Gaps:	98/553 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 IWPMPTGKECTISHRRVRFDPWKVRFHVVAPGEAATQFLRETNRLFVSNLLKECI-RNCTLE--- 153
            :||:|.  |.:..:..:..||....  :||.....:..:|.....::..:.|... |...|.
plant    33 LWPLPA--EFSFGNETLSVDPTVTL--IVAGNGGGSLIIRAAFDRYMGIIFKHASGRGSLLSRIR 93

  Fly   154 ---------TSKQILVRSTVANESLVLDWPTDESYALVVRTTETATFV---DIQATTVYGARHAF 206
                     ||.:|:|.|    :|..|....||||.|:|......:.|   .|:|.|||||....
plant    94 FLKMVEYDITSLKIVVHS----DSEELQLGVDESYTLMVSKKNEQSIVGAATIEANTVYGALRGL 154

  Fly   207 ETLSNLVTGSLSNGLLMVTTA--NITDRPAFSHRGVLLDTARNFVPLKFIRSTLDAMAASKLNVL 269
            ||.|.|.........:.:..|  .|.|:|.|.:||:|:||:|:::|:..|:..:::|:.:|||||
plant   155 ETFSQLCAFDYITKSVQIYKAPWYIQDKPRFGYRGLLIDTSRHYLPIDVIKQIIESMSFAKLNVL 219

  Fly   270 HWHVVDTHSFPLEITRVPEMQRYGAYSSSQTYSRQDALNLVKYARLRGIRILIEIDGPSHAGNGW 334
            |||:||..|||||....|.:.: ||||..:.|:.:||..:|::|::|||.::.|:|.|.||.:
plant   220 HWHIVDEQSFPLETPTYPNLWK-GAYSRWERYTVEDASEIVRFAKMRGINVMAEVDVPGHAES-- 281

  Fly   335 QWGPAAGLGNMSVCLNQSPWRRFCVQPPCGQLNPLNDHMYAVLKEIFEDVAEVGAPEETLHMGGD 399
             ||  .|..::...|:       |.:|    |:...:..:.|:..|..|:.:: .|.|..|:|||
plant   282 -WG--TGYPDLWPSLS-------CREP----LDVTKNFTFDVISGILADMRKI-FPFELFHLGGD 331

  Fly   400 EVFLPCWNNTDEIRDGMRARGY---DLSEQSFLRLWSQFHQRNLNAWDEINERMYPGIKEPKSVI 461
            ||...||.||..:::.::.|.:   |..:...||.......:|   |..:|
plant   332 EVNTDCWKNTTHVKEWLQGRNFTTKDAYKYFVLRAQQIAISKN---WTPVN-------------- 379

  Fly   462 IWSSHLTNPRYIETY--LPKE---RFIIQTWVESQDALNRELLQRGYRLIVSTKNAWYLDHGFWG 521
             |.         ||:  ..|:   |.:||.|:.|.  :.::.:.:|:|.|.|.:..|||||
plant   380 -WE---------ETFSSFGKDLDPRTVIQNWLVSD--ICQKAVAKGFRCIFSNQGYWYLDH---- 428

  Fly   522 STSYYNWRTVYSSGMPVGRSKDQ-----VLGGEVCMWSEYVDQNSLESRIWPRAGAAAERMWSNP 581
              ....|..||:: .|:...:|.     |:|||||||.|..|.:.:...|||||.||||||||..
plant   429 --LDVPWEEVYNT-EPLNGIEDPSLQKLVIGGEVCMWGETADTSVVLQTIWPRAAAAAERMWSTR 490

  Fly   582 KSSA-----LLAQRRFYRYRERLLARGIHADAV 609
            ::.:     |.|..|.:.:|..|..||:.|..|
plant   491 EAVSKGNITLTALPRLHYFRCLLNNRGVPAAPV 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hexo2	NP_525081.1	Glycohydro_20b2	93..212	CDD:291511	36/134 (27%)
Hexo2	NP_525081.1	GH20_HexA_HexB-like	235..603	CDD:119332	123/385 (32%)
HEXO1	NP_567017.2	Glycohydro_20b2	33..160	CDD:373334	36/134 (27%)
HEXO1	NP_567017.2	GH20_HexA_HexB-like	185..517	CDD:119332	123/385 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54329
OrthoDB	1	1.010	-	-		D545162at2759
OrthoFinder	1	1.000	-	-		FOG0001678
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22600
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X846
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930