Protein Alignment Hexo2 and hexb

DIOPT Version :9

• Sequence 1: NP_525081.1
• Gene: Hexo2 / 31808
• FlyBaseID: FBgn0041629
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_009299722.1
• Gene: hexb / 323613
• ZFINID: ZDB-GENE-030131-2333
• Length: 544
• Species: Danio rerio
• Alignment Length: 605
• Identity: 171/605 - (28%)
• Similarity: 284/605 - (46%)
• Gaps: 117/605 - (19%)

  Fly    66 MVAGLQYAP--------------EIFESQRDC-RLSCGKYGAIWPMPTGKECTISHRRVRFDPWK 115
            |:..|::.|              ::||.|::. .:|      :||:|...:.:    .|.|....
Zfish     1 MLCLLKFTPLFLVVAVCHGWLFGDLFEKQKELDEIS------LWPLPQKYQSS----AVAFKLSA 55

  Fly   116 VRFHVVAPGEA----ATQFLRETNRLFVSNLLKECIRNCTLETSKQILVRSTVANESLVL----- 171
            ..|.:|...::    :...|....|.:...:..|..|.   |.|::....|.::...:.:
Zfish    56 ASFQIVHAKQSTAGPSCSLLENAFRRYFEYMFGELKRQ---EKSRKKAFDSDLSELQVWITSADP 117

  Fly   172 ---DWP---TDESYALVVRTTETATFVDIQATTVYGARHAFETLSNLVTGSLSNGLLMVTTANIT 230
               .:|   |||||:|.|..|...    ::|..|:||....||.|.||... ..|:..:...:|:
Zfish   118 ECDGYPSLRTDESYSLSVDETSAV----LKAANVWGALRGLETFSQLVYED-DYGVRNINKTDIS 177

  Fly   231 DRPAFSHRGVLLDTARNFVPLKFIRSTLDAMAASKLNVLHWHVVDTHSFPLEITRVPEM--QRYG 293
            |.|.|:|||:|||::|:|:|||.|.:.|:|||.:|.||.|||:||..|||......||:  :|.|
Zfish   178 DFPRFAHRGILLDSSRHFLPLKVILANLEAMAMNKFNVFHWHIVDDPSFPFMSRTFPELSQKRKG 242

  Fly   294 AYSS-SQTYSRQDALNLVKYARLRGIRILIEIDGPSHAGNGWQWGPAAGLGN-MSVCLN-QSPWR 355
            ||.. :..|:..|...::::||:||||::.|.|.|.|..:   ||  .|:.: ::.|.: .||..
Zfish   243 AYHPFTHVYTPSDVKMVIEFARMRGIRVVAEFDTPGHTQS---WG--NGIKDLLTPCYSGSSPSG 302

  Fly   356 RFCVQPPCGQLNPLNDHMYAVLKEIFEDVAEVGAPEETLHMGGDEVFLPCWNNTDEIRDGMRARG 420
            .|      |.:||:.:..|..:.::|::::.| .|:..:|:|||||...||.:..:|:..|..:|
Zfish   303 SF------GPVNPILNSSYEFMAQLFKEISTV-FPDAYIHLGGDEVDFSCWKSNPDIQKFMNQQG 360

  Fly   421 YDLSEQSFLRLWSQFHQRNLN----------AWDEINERMYPGI--KEPKSVIIWSSHLTNPRYI 473
            :.   ..:.:|.|.:.||.|:          .|.|:.:.   |:  |....:.:|..   .|:|
Zfish   361 FG---TDYSKLESFYIQRLLDIVAATKKGYMVWQEVFDN---GVKLKADTQIHVWKG---RPQY- 415

  Fly   474 ETYLPKERFIIQTWVESQDALNRELLQRGYRLIVSTKNAWYLDHGFWGSTSYYNWRTVYSSGMP- 537
                             ||.: .::...|:..::||  .|||:...:|.    :|..:|.:...
Zfish   416 -----------------QDEM-AKVTAAGFSALLST--PWYLNRVSYGQ----DWVDIYKADPQN 456

  Fly   538 ---VGRSKDQVLGGEVCMWSEYVDQNSLESRIWPRAGAAAERMWSNPKSSAL-LAQRRFYRYRER 598
               ....|..|:|||.|:|.||||..:|..|:||||.|.|||:||:...:.: .|..|..::|.|
Zfish   457 FNGTDAQKKLVIGGEACLWGEYVDATNLTPRLWPRASAVAERLWSDASVTDVGNAYTRLAQHRCR 521

  Fly   599 LLARGIHADAVIPHWCVLHE 618
            ::.|||.|:.:....| .||
Zfish   522 MVRRGIPAEPLFVGHC-RHE 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hexo2	NP_525081.1	Glycohydro_20b2	93..212	CDD:291511	30/133 (23%)
		GH20_HexA_HexB-like	235..603	CDD:119332	121/389 (31%)
hexb	XP_009299722.1	Glycohydro_20b2	37..160	CDD:291511	30/133 (23%)
		GH20_HexA_HexB-like	182..526	CDD:119332	121/389 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580457
Domainoid	1	1.000	191	1.000	Domainoid score	I3177
eggNOG	1	0.900	-	-		E1_COG3525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	220	1.000	Inparanoid score	I3531
OMA	1	1.010	-	-		QHG54329
OrthoDB	1	1.010	-	-		D164123at33208
OrthoFinder	1	1.000	-	-		FOG0001678
OrthoInspector	1	1.000	-	-		mtm6615
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22600
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2560
SonicParanoid	1	1.000	-	-		X846
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.940