Protein Alignment Hexo2 and Hexo2

DIOPT Version :10

• Sequence 1: NP_525081.1
• Gene: Hexo2 / 31808
• FlyBaseID: FBgn0041629
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_061506877.1
• Gene: Hexo2 / 1268907
• VectorBaseID: AGAMI1_003439
• Length: 605
• Species: Anopheles gambiae
• Alignment Length: 635
• Identity: 273/635 - (42%)
• Similarity: 393/635 - (61%)
• Gaps: 57/635 - (8%)

  Fly    11 CFCSAVGSLLLLSLLSFAVGAALTRADDVGSDADAGSASRKWLCSRTDICTAEGEMVAGLQYAPE 75
            |..|..|.::|  :|..|...|::...|:           .:.|:..:.|.   .:....:.|.|
Mosquito     3 CAMSKYGIVVL--VLFHAFQHAVSCLKDI-----------SYKCTNEEQCV---RVYGNTKSASE 51

  Fly    76 --IFESQRDCRLSCGKYGAIWPMPT-----GKECTISHRRVRFDPWKVRFH--VVAPGEAATQFL 131
              :|.:..:|||.|||||.:||.||     |||.|:      .:|..:||.  .:......|..|
Mosquito    52 SHVFSTLSNCRLLCGKYGPLWPRPTGHVTLGKETTV------VNPLNLRFEQDFINQTTEGTTIL 110

  Fly   132 RETNRLFVSNLLKECIRNCTLETS--KQILVRSTVANESLVLDWPTDESYALVVRTTETATFV-D 193
            ||....|:.||.|........|::  ..|:::..:.:....|.|..||||.|.:......|.| .
Mosquito   111 REIKMYFLRNLRKAFQTQILHESTPGMPIIIKIQITSNETNLSWYVDESYKLKISIENLTTVVTT 175

  Fly   194 IQATTVYGARHAFETLSNLVTGSLSNGLLMVTTANITDRPAFSHRGVLLDTARNFVPLKFIRSTL 258
            |:|.|::|.||.||||..|.| ::::.:.:::.|||.|:|.::|||:|:|||||::|:|.::..:
Mosquito   176 IEAKTIFGTRHGFETLLQLFT-TVNSSVNILSQANIIDQPIYAHRGLLIDTARNYIPIKCLKRQI 239

  Fly   259 DAMAASKLNVLHWHVVDTHSFPLEITRVPEMQRYGAYSSSQTYSRQDALNLVKYARLRGIRILIE 323
            |||||||.||.|||:.||.|||::...||||..|||||..:.||:.|..:::|||:.||||:::|
Mosquito   240 DAMAASKFNVFHWHITDTQSFPMQFDTVPEMVFYGAYSKEEVYSQNDIKSIIKYAKYRGIRVILE 304

  Fly   324 IDGPSHAGNGWQWGPAAGLGNMSVCLNQSPWRRFCVQPPCGQLNPLNDHMYAVLKEIFEDVAEVG 388
            :|.|:||||||||||...|||::||:||.|||.||::||||||||:|.::|.||::|::|:||:.
Mosquito   305 LDAPAHAGNGWQWGPEKDLGNLAVCVNQKPWRNFCIEPPCGQLNPINPNLYTVLQQIYKDIAEMN 369

  Fly   389 APEETLHMGGDEVFLPCWNNTDEIRDGMRARGYDLSEQSFLRLWSQFHQRNLNAWD--------- 444
            ..|..:||||||||..|||.|.||.:.:.......:||.||.:||:|.::.||.||
Mosquito   370 KEESVIHMGGDEVFFGCWNATAEIINYLMDHNLGRTEQDFLTMWSKFQKKVLNLWDNARRANGSA 434

  Fly   445 ---EINERMYPGIKEPKSVIIWSSHLTNPRYIETYLPKERFIIQTWVESQDALNRELLQRGYRLI 506
               ..||...|       ||:|||.||:|..|:.:|.|.|::||||:.|...:.:||.:.||:||
Mosquito   435 YSASTNEHSSP-------VILWSSRLTDPLVIDKFLSKNRYVIQTWLPSSSTIPKELQKLGYKLI 492

  Fly   507 VSTKNAWYLDHGFWGSTSYYNWRTVYSSGMPVGRSKDQVLGGEVCMWSEYVDQNSLESRIWPRAG 571
            ||||:||||||||||.|:||.|:.||.:.:|.|..   :||||||:|:||:|:.|::.|.||||.
Mosquito   493 VSTKDAWYLDHGFWGVTTYYTWKKVYDNQLPKGNG---ILGGEVCVWTEYIDEYSIDGRTWPRAA 554

  Fly   572 AAAERMWSNPKSSALLAQRRFYRYRERLLARGIHADAVIPHWCVLHEGQC 621
            |||||:||||::.|:.|:.||:.:||||:.|||..:|:.|.||..:|.||
Mosquito   555 AAAERLWSNPETKAIDAESRFFCHRERLIIRGIQPEALAPRWCEQNEKQC 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hexo2	NP_525081.1	Glyco_hydro_20b	93..212	CDD:446174	40/128 (31%)
		GH20_HexA_HexB-like	235..603	CDD:119332	195/379 (51%)
Hexo2	XP_061506877.1	None