DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32523 and prss60.1

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	283	Identity:	88/283 - (31%)
Similarity:	129/283 - (45%)	Gaps:	46/283 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWTTLWTVLLLLLCGVQVILGQDVAQNQSESA-IEPRIVGGIKAKQGQFPHQISLR--LRGEHYC 62
            ||......|.||||    :.|.....|....| :..|||||:.|..|.:|.|:||.  :.|.|:|
Zfish     1 MWRFTCVSLALLLC----VQGSHSQLNVCGLAPLNNRIVGGVNAFDGSWPWQVSLHSPIYGGHFC 61

  Fly    63 GGVIISATHVITAGHCVKHGNDVVPADLWSIQAGSLLL-----SSDGVRI-----PVAEVIMHPN 117
            ||.:|::..|:||.||:..           |...|||:     :..||..     .|:.:.:||:
Zfish    62 GGSLINSEWVLTAAHCLPR-----------ITTSSLLVFLGKTTQQGVNTYEINRTVSVITVHPS 115

  Fly   118 YAT-GGHNDLAVLRLQSPLTFDANIAAIQLATEDP--PNCVAVDISGWGNI------AEKGPLSD 173
            |.. ...||:|:|.|.|.:||...|..:.||.::.  ||..:..|:|||||      ...|.|.:
Zfish   116 YNNLTNENDIALLHLSSAVTFSNYIRPVCLAAQNSVFPNGTSSWITGWGNIQLGVNLPAPGILQE 180

  Fly   174 SLLFVQVTSISRGACRWMFYS-RLPETMICL-LHSKNSGACYGDSGGPATYGGKVVGLASLLLGG 236
            :::.|    :....|..:..| .:...|||. |.......|.||||||......:|.:.|.:...
Zfish   181 TMIPV----VPNDQCNALLGSGSVTNNMICAGLLQGGRDTCQGDSGGPMVSKQCLVWVQSGITSW 241

  Fly   237 GCGRA---APDGYLRISKVRAWI 256
            |.|.|   :|..|.|:|:.::||
Zfish   242 GYGCADPYSPGVYTRVSQYQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	76/245 (31%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	64/204 (31%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	76/245 (31%)
		Tryp_SPc	34..267	CDD:238113	77/246 (31%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587857
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840