DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and Tmprss11a

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_038948511.1	Gene:	Tmprss11a / 686581	RGDID:	1596322	Length:	387	Species:	Rattus norvegicus

Alignment Length:	268	Identity:	77/268 - (28%)
Similarity:	119/268 - (44%)	Gaps:	43/268 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 CGVQVILGQDVAQNQSESAIEPRIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHVITAGHC 78
            ||.:.|           ..|..|||.|..|.:|.:|.|:||:....|.|||.:|....|:||.||
  Rat   144 CGKRAI-----------PLIANRIVSGNPAAKGAWPWQVSLQRNNIHQCGGTLIGNMWVVTAAHC 197

  Fly    79 VKHGNDVVPADLWSIQAGSLLLSSDGVRIPVAEVIMHPNYATGGH-NDLAVLRLQSPLTFDANIA 142
            .:  .:..|.. |::..|: .::...::..|..:|||..|..... :|:|:::....:||...:.
  Rat   198 FR--TNANPRQ-WTLSFGT-TINPPLMKREVRRIIMHEKYRPPARDHDIALVQFSPRVTFSDEVR 258

  Fly   143 AIQL---ATEDPPNCVAVDISGWGNIAEKGPLSDSLLFVQVTSISRGAC--RWMFYSRLPETMIC 202
            .|.|   :...|||. .|.|:|:|.:...|...:.|...:|..||...|  |.::.:.:...|.|
  Rat   259 RICLPEPSASFPPNS-TVYITGFGALYYGGESQNELREARVQIISNDVCKQRHVYGNEIKRGMFC 322

  Fly   203 LLHSKNSG-------ACYGDSGGPATYGGK-----VVGLASLLLGGGCG-RAAPDGYLRISKVRA 254
                  :|       ||.||||||......     ::|:.|  .|..|| :..|..|.:::..|.
  Rat   323 ------AGFLEGIYDACRGDSGGPLVVRDDKDTWYLIGIVS--WGDNCGQKNKPGVYTQVTYYRR 379

  Fly   255 WIAEKAGL 262
            |||.|.||
  Rat   380 WIASKTGL 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	67/238 (28%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	56/194 (29%)
Tmprss11a	XP_038948511.1	SEA	35..133	CDD:396113
Tmprss11a	XP_038948511.1	Tryp_SPc	156..384	CDD:238113	69/240 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910