Protein Alignment CG32523 and PRSS22

DIOPT Version :10

• Sequence 1: NP_728401.1
• Gene: CG32523 / 318071
• FlyBaseID: FBgn0052523
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 77/244 - (31%)
• Similarity: 123/244 - (50%)
• Gaps: 30/244 - (12%)

  Fly    36 RIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHVITAGHCVKHGNDVVPADLWSIQAGSLLL 100
            |:|||..:...::|..:|::..|.|:|.|.::::..||||.||.|  :::....|:|:..|:..|
Human   157 RVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFK--DNLNKPYLFSVLLGAWQL 219

  Fly   101 SSDGVR---IPVAEVIMHPNYA--TGGHNDLAVLRLQSPLTFDANIAAIQLATED---PPN--CV 155
            .:.|.|   :.||.|..||.|:  .|...|:|::||:..:.|...:..|.|....   |||  |.
Human   220 GNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCW 284

  Fly   156 AVDISGWGNIAEKGPL--SDSLLFVQVTSISRGACRWMFY-----SRLPETMICLLHSKNS-GAC 212
               |||||:|.:..||  ..:|..::|..|....|..:::     ..:.|.|:|..:.:.. .||
Human   285 ---ISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDAC 346

  Fly   213 YGDSGGPATYGGKVVG---LASLL-LGGGCG-RAAPDGYLRISKVRAWI 256
            .||||||...  :|.|   ||.:: .|.||. |..|..|:.:|..|:|:
Human   347 LGDSGGPLMC--QVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWV 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	61/199 (31%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	76/243 (31%)