DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32523 and c1s

DIOPT Version :9

Sequence 1:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_002941253.2	Gene:	c1s / 613055	XenbaseID:	XB-GENE-995410	Length:	691	Species:	Xenopus tropicalis

Alignment Length:	271	Identity:	71/271 - (26%)
Similarity:	110/271 - (40%)	Gaps:	49/271 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LCGVQVILGQDVAQNQSESAIEPRIVGGIKAKQGQFPHQISLRLRGEHYCGGVIISATHVITAGH 77
            :|||          :||:.:  .||.||.:||.||||..|  :.......||.:||...|:||.|
Frog   425 VCGV----------HQSDKS--GRIFGGTRAKPGQFPWMI--QFTDIELGGGSLISDRWVLTAAH 475

  Fly    78 CVKHGNDVVPADLWSIQAGSLL-------LSSDGVRIPVAEVIMHPNYA----TGGH----NDLA 127
                   ||...::....|.::       |.|...|:...::|:||.|.    |.|.    ||:|
Frog   476 -------VVNKKIFPTMFGGVMKFFPNTNLQSQEKRLQAKKIIIHPLYQDNEDTEGQSNFDNDIA 533

  Fly   128 VLRLQSPLTFDANIAAIQLATED--PPNCVAVDISGWGNIAEKGPLSDSLLFVQVTSISRGACRW 190
            :::|...:...:.|:.|.|....  |.......|:|||. .||...:.:|.|..::..|...|:.
Frog   534 LVQLTKKVKLGSCISPICLPRRGLAPVVNEVATIAGWGK-TEKRESAVNLQFASISLSSMDKCKK 597

  Fly   191 MFYSR--LPETMICLLHSKNSGACYGDSGGPATY----GGKVVGLASLLLGG--GCGRAAPDGYL 247
            ....:  ....|:|........:|.||||||..:    ....:.:|.::..|  .||....  |.
Frog   598 ATGGKGYFTPNMLCAGSDVGKDSCNGDSGGPLMFTDPQDSSKMYMAGIVSWGPRDCGTYGL--YT 660

  Fly   248 RISKVRAWIAE 258
            ::.....||.|
Frog   661 KVDNYLDWIEE 671

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	63/244 (26%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	55/200 (28%)
c1s	XP_002941253.2	CUB	21..131	CDD:238001
		FXa_inhibition	145..173	CDD:405372
		CUB	177..288	CDD:238001
		PHA02927	301..>436	CDD:222943	5/22 (23%)
		Tryp_SPc	436..669	CDD:214473	63/244 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910